Project Grant K24HL179410
- The Regents of the University of Michigan were awarded a $207,342 Project Grant from the National Heart Lung and Blood Institute's Cardiovascular Diseases Research program (CFDA 93.837) on September 12, 2025. The goal of this 5-year program is to enhance research training and career development opportunities for Emergency Medicine (EM) resident investigators at the University of Michigan. The program will recruit and train 2 outstanding EM resident trainees annually, providing them with 12...
- This $1,380,474 federal Project Grant awarded on September 24, 2025 by the National Heart, Lung, and Blood Institute (CFDA 93.837 Cardiovascular Diseases Research) aims to improve the care of patients with acute heart and lung diseases. The University of Michigan will develop data-driven models to support improved decision-making for intensive care unit (ICU) triage and inpatient bed assignment. The project will identify determinants of triage and bed assignment, develop a clinical decision...
- This federal Project Grant award of $747,281 from the National Heart Lung and Blood Institute (CFDA 93.837 Cardiovascular Diseases Research) supports the development of a real-time, non-invasive technique to characterize the mechanical properties of blood clots (thrombi) as they age. The project aims to utilize ultrasound-responsive nanodroplets that can transition into microbubbles when exposed to focused ultrasound, a process known as acoustic droplet vaporization (ADV). By leveraging ADV, the...
- This Project Grant award for $713,538 from the National Heart, Lung, and Blood Institute (CFDA 93.837 Cardiovascular Diseases Research) supports research to investigate metabolic reprogramming as a novel therapeutic approach for thrombotic cardiovascular disease. The key objectives are to explore how inhibiting the cytosolic malic enzyme 1 (ME1) in platelets and leukocytes can reduce their hyperactivation and susceptibility to arterial thrombosis, while minimizing bleeding risk compared to...
- This federal Project Grant award of $429,000.00 from the National Heart Lung and Blood Institute (CFDA 93.837 Cardiovascular Diseases Research) aims to develop an efficient, contrast-free, 3D whole-lung low-field magnetic resonance imaging (MRI) protocol for the detection of pulmonary embolism (PE). The project, awarded to the Regents of the University of Michigan, will leverage advancements in low-field MRI hardware and deep learning techniques to create a rapid, comfortable, and radiation-free...
- This federal Project Grant award of $101,360.00 was provided by the National Heart Lung and Blood Institute under the Cardiovascular Diseases Research program (CFDA 93.837) to The Johns Hopkins University. The grant will support a postdoctoral research project led by Dr. Andrew Davis that aims to use observational data and causal inference methods to develop evidence-based interventions for reducing hospital readmissions among survivors of pneumonia with respiratory failure. The project's...
- This Project Grant award from the National Heart Lung and Blood Institute (CFDA 93.837 - Cardiovascular Diseases Research) provides $1,061,189 to the Regents of the University of Michigan to conduct research on immune crosstalk in lung injury and fibrosis. The key objectives are to study epithelial cell regulation of fibrosis and its interaction with myeloid cells, uncover mechanisms for impaired innate immunity against gram-positive infections in fibrosis, test delivery of targeted therapeutics...
- This federal Project Grant award, valued at $272,226.00, was granted by the National Heart Lung and Blood Institute under the Cardiovascular Diseases Research program (CFDA 93.837). The project aims to determine how clinician and scheduling characteristics impact patient outcomes, and explore the moderating effect of patient characteristics on these relationships, for mechanically ventilated adults in intensive care units. The project will conduct a novel secondary analysis utilizing a unique...
- This $147,486.00 Project Grant award from the National Heart Lung and Blood Institute (CFDA 93.837 - Cardiovascular Diseases Research) supports research to investigate the role of high-fat diet in hematopoiesis (blood cell formation) and clonal hematopoiesis, a condition associated with increased risk of myeloid diseases like myelodysplastic syndrome and acute myeloid leukemia. The award was made to the Regents of the University of Michigan, Ann Arbor for a project period running from Jul 9,...
- This federal Project Grant award of $701,791 from the National Heart Lung and Blood Institute (CFDA 93.837 - Cardiovascular Diseases Research) supports research to investigate the role of neddylation, a post-translational modification, in protecting endothelial cell integrity and function. The research aims to establish the pathophysiological significance of neddylation in the endothelium and identify key downstream effectors. The University of Nebraska, Lincoln is the awardee and will utilize...
This Project Grant award, titled "DEVELOPING IMPLEMENTATION SCIENCE EXPERTISE IN CARDIOVASCULAR HEALTH SERVICES RESEARCH", is funded by the National Heart, Lung, and Blood Institute under the Cardiovascular Diseases Research program (CFDA 93.837). The $133,085 grant, awarded on September 1, 2025, supports research activities at the University of Michigan to improve the management of anticoagulant medication and increase the use of evidence-based outpatient treatment for low-risk pulmonary embolism. The research leverages the awardee's ongoing NIH-funded projects and focuses on developing implementation science expertise, including through mentoring the next generation of patient-oriented researchers. The award aims to advance evidence-based practices and reduce unnecessary risks for patients with cardiovascular conditions.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $133.1k | 8/26/25 |