This $137,219 Project Grant awarded by the National Heart, Lung, and Blood Institute (CFDA 93.837 - Cardiovascular Diseases Research) supports a mentoring and patient-oriented research program focused on sickle cell disease-related kidney disease at the University of Illinois.
The principal investigator, Dr. Santosh L. Saraf, aims to leverage existing sickle cell disease cohorts and collaborations to train the next generation of clinician-scientists. The proposed research investigates genetic factors and complement activation underlying the progression of chronic kidney disease in sickle cell patients. This award provides Dr. Saraf with protected time to expand his mentoring efforts and advance the understanding of risk factors and treatment targets for this significant complication affecting over half of adults with sickle cell disease.
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