Project Grant K24AI190403
- The federal Project Grant award from the National Institute of Allergy and Infectious Diseases (CFDA 93.855 - Allergy and Infectious Diseases Research) is providing $209,757 to The Trustees of Columbia University in the City of New York, Health Sciences Division, from September 15, 2025 to August 31, 2030. The funding supports mentorship and training to develop a new cadre of researchers focused on addressing the challenges of multidrug-resistant tuberculosis (MDR-TB) within the global HIV...
- This $1,173,748.00 Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID), under the Allergy and Infectious Diseases Research program (CFDA 93.855), will fund research on the role of asymptomatic tuberculosis (TB) in disease transmission. The research aims to improve understanding of when individuals become infectious and where transmission is occurring, particularly in community settings outside of household contacts. Key areas of focus include characterizing...
- This Project Grant award of $821,087 from the National Institute of Allergy and Infectious Diseases (NIAID), under the Allergy and Infectious Diseases Research program (CFDA 93.855), will fund research to examine the relationship between latent tuberculosis infection (LTBI) and the risk of developing diabetes mellitus and cardiovascular disease. The key objectives are to: 1) Estimate the association between LTBI and indicators of diabetes and cardiovascular disease; 2) Determine if established...
- This $209,408 Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID), under the Allergy and Infectious Diseases Research (CFDA 93.855) program, supports a research project to characterize the role of unconventional T cell subsets in the immune response to Mycobacterium tuberculosis (MTB) infection using a non-human primate model. The goal is to gain a better understanding of these niche T cell populations in the lung granulomas during the early stages of MTB...
- This Project Grant award of $375,996.00 from the National Institute of Allergy and Infectious Diseases (NIAID), under the Allergy and Infectious Diseases Research Federal Grant Program (CFDA 93.855), supports research to assess the potential carriage state of Mycobacterium tuberculosis (MTB) in the upper respiratory tract of individuals who have been exposed to tuberculosis (TB) but do not display active disease. The research aims to understand the mechanisms by which the majority of people...
- This $162,000 Project Grant award from the National Institute of Allergy and Infectious Diseases (CFDA 93.855 - Allergy and Infectious Diseases Research) supports research to characterize the role of plasmacytoid dendritic cells (PDCs) in Mycobacterium tuberculosis (MTB) infection. The research aims to quantify PDC trafficking and activation in the lungs during MTB infection, and determine how PDC-driven type I interferon responses impact MTB control. The project will leverage a mouse model that...
- This Project Grant award of $3,145,850.00 was provided by the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research (CFDA 93.855) federal grant program. The award supports research at The Johns Hopkins University to investigate macrophage senescence as a driver of granuloma failure and necrosis in pulmonary tuberculosis (TB) and TB/HIV coinfection. Key objectives include understanding the role of stress-induced senescence in myeloid...
- The University of Washington received a $188,760 Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research (CFDA 93.855) program. The grant supports research to investigate the role of the lung inflammatory environment and cellular milieu in controlling Mycobacterium tuberculosis (MTB) infection and preventing tuberculosis (TB) disease. Specifically, the research will test the hypothesis that interferon gamma-activated...
- This $193,375 Project Grant, awarded by the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), supports research to identify bacterial determinants that may contribute to variable treatment responses for tuberculosis (TB). The project, conducted by researchers at the Harvard T.H. Chan School of Public Health, aims to investigate the effects of clinically prevalent variants in the ESX1 secretion system on TB...
- This $854,000 Project Grant awarded by the National Institute of Allergy and Infectious Diseases (NIAID), under the Allergy and Infectious Diseases Research Federal Grant Program (CFDA 93.855), aims to assess post-tuberculosis (TB) lung disease in TB patients with and without HIV coinfection. The project will utilize novel positron emission tomography (PET) imaging techniques, such as 11C-rifampin PET, to longitudinally profile lesional characteristics and antibiotic exposures in animal models...
This Project Grant award, titled "ENHANCING RESEARCH AND MENTORING SKILLS IN TUBERCULOSIS (EARN TB)", is provided by the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research Federal Grant Program (CFDA 93.855). The $192,027 award, effective August 4, 2025 through July 31, 2030, supports Dr. Russell Kempker at Emory University to: The research leverages Emory University's long-standing collaboration with the National Center for Tuberculosis and Lung Diseases in Tbilisi, Georgia, and an ongoing NIAID R01 study led by Dr. Kempker. The proposed work includes evaluating the impact of surgical removal of MTB-diseased lung on decreasing systemic inflammation, and utilizing enhanced spatial transcriptomics methods.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $192.0k | 8/4/25 |