Project Grant K23NS144704
- Federal Grant Award Summary Baylor College of Medicine received a $124,106 Project Grant from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853), with an award date of April 1, 2026 and completion date of March 31, 2028. The award supports research investigating the mechanisms of neurological manifestations in Myotonic Dystrophy Type 1 (DM1), a progressive neuromuscular...
- The University of Rochester received a $332,792 Project Grant award from the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846), effective May 1, 2026, through April 30, 2031. The project, titled "Drivers of Repeat Instability in Myotonic Dystrophy," delivers research investigating the molecular mechanisms underlying germline and somatic repeat instability in Myotonic...
- Federal Project Grant Award Summary The University of North Carolina at Chapel Hill received a $439,588 Project Grant from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853), awarded June 22, 2026, with completion targeted for May 31, 2028. The award funds development of gene therapy approaches to treat cerebellar CACNA1A disorders—a group of neurodevelopmental and...
- Grant Award Summary The National Institute of Neurological Disorders and Stroke (NINDS) awarded The Trustees of Columbia University in the City of New York $227,640 under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853) for a two-year project running from November 1, 2026 through October 31, 2028. The research investigates CCR5 (C-C chemokine receptor type 5) as a combination therapy target for spinal muscular atrophy (SMA), a devastating...
- Federal Grant Award Summary The National Institute of Neurological Disorders and Stroke (NINDS) awarded a $341,129 Project Grant to the Research Institute at Nationwide Children's Hospital effective July 1, 2026, through June 30, 2031, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853). The award funds a Training Program in Basic and Translational Gene Therapy Research designed to train the next generation of clinicians and scientists...
- This K08 Mentored Research Career Development Award from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853) provides $221,400 in federal funding to The Children's Hospital of Philadelphia Research Institute through May 15, 2026, with a completion date of March 31, 2031. The award supports an intensive training and career development program designed to position the...
- Federal Grant Award Summary The National Institute of Neurological Disorders and Stroke (NINDS) awarded $129,170 to Massachusetts General Hospital, effective August 1, 2025 through July 31, 2027, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853). This Project Grant supports training and research to elucidate the genetic and epigenetic mechanisms underlying somatic expansion of short tandem repeats (STRs) in repeat expansion diseases,...
- Federal Project Grant Award Summary Albany Medical College received a $562,051 Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853), effective March 6, 2026, with a completion date of February 28, 2031. This research initiative investigates the modulation of the Hippo pathway as a novel therapeutic approach for Charcot-Marie-Tooth Disease Type 1A...
- Federal Project Grant Award Summary The University of Missouri System received a $574,083 Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853), effective March 15, 2026, with a completion date of January 31, 2031. The award funds the development of a vector-based therapeutic treatment for Charcot-Marie-Tooth disease type 2E (CMT2E), a common...
- Federal Project Grant Summary The Regenerative Research Foundation received a $233,550 Project Grant award dated June 1, 2026, from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853). The award supports a two-year research initiative (completion by May 31, 2028) to model myotonic dystrophy types 1 and 2 (DM1 and DM2) neuropathology using human induced pluripotent stem...
Dr. Samuel Carrell, Assistant Professor of Neurology at Virginia Commonwealth University (VCU), received a $194,907 Mentored Career Development Award from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853), awarded July 10, 2026, with completion targeted for June 30, 2031. This award supports Dr. Carrell's research training and transition to independence as a physician-scientist focused on identifying genetic modifiers of myotonic dystrophy type 1 (DM1), a neuromuscular disorder characterized by significant clinical variability in disease severity and presentation. The project delivers research and mentorship services conducted through VCU's Center for Inherited Myology Research (CIMR) under the guidance of primary mentor Dr. Nicholas Johnson and co-mentors specializing in human genetics and biostatistics. The research leverages the Myotonic Dystrophy Clinical Research Network for patient cohorts and international collaborations to develop novel biomarkers and therapeutic approaches. Deliverables include training in translational research methodologies, clinical data analysis, pre-clinical disease modeling, and the preparation of Dr. Carrell for independent National Institutes of Health (NIH) R01-level funding as a researcher supporting the muscular dystrophy patient population served through the Muscular Dystrophy Association clinic.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $194.9k | 7/7/26 |