This Project Grant award from the National Institute of Mental Health (NIMH), under the Mental Health Research Grants program (CFDA 93.242), provides $434,421 to The Feinstein Institutes for Medical Research to conduct research on the development of cerebellar-cortical functional connectivity in youth and its prediction of psychosis. The key objectives of this 4-year project are to: 1) chart the normal development curves of cerebellar-cortical connectivity from childhood to early adulthood using...
The National Institute of Mental Health (NIMH) awarded a $1,453,943 Project Grant under the Mental Health Research Grants program (CFDA 93.242) to the University of California, Los Angeles (UCLA) for the period of June 1, 2025 to May 31, 2028. The grant will fund the development of an integrated, portable sensor suite to concurrently record neural activity, physiological arousal, motor signals, and physical interactions in social environments. The project aims to track neuro-behavioral attention...
This Project Grant award from the National Institute of Mental Health (NIMH), under the Mental Health Research Grants program (CFDA 93.242), will provide $3,085,041 to the University of Pittsburgh to conduct longitudinal research on adolescent brain maturation and its relationship to psychopathology. The research aims to: Characterize the longitudinal trajectory of neuropil growth/contraction using 3D whole-brain phosphorus magnetic resonance spectroscopy (31P MRS). Elucidate the relationship...
The National Institute of Mental Health (NIMH) awarded a $845,163 Project Grant under the Mental Health Research Grants (CFDA 93.242) program to The Feinstein Institutes for Medical Research. The project aims to develop a low-cost, low-burden approach that produces accurate, objective markers of psychosis severity using automated speech and language analysis. This would serve as "vital signs" for monitoring psychosis in a longitudinal clinical context. The project will first build a...
This Project Grant award from the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242) supports research to identify biomarkers in the cerebellar-cortical circuitry that can predict treatment response to antipsychotic medication in patients with early psychosis. The $519,558 award, which runs from June 2025 to April 2030, will enable the Feinstein Institutes for Medical Research to validate the identified predictive biomarker in a larger sample...
This Project Grant award of $857,903 from the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242) is funding research to leverage computationally derived measures of individual differences in learning and decision-making to predict psychiatric diagnosis, symptoms, and changes in symptom severity over time. The primary goal is to develop reliable, robust computational measures of cognitive processes that are meaningfully relevant to psychiatric...
This federal Project Grant award from the National Institute of Mental Health (NIMH), under CFDA Program 93.242 Mental Health Research Grants, provides $148,423 to the University of Kansas Center for Research Inc. to study sensory feedback mechanisms of fine and gross motor control in individuals with autism spectrum disorder (ASD), with and without intellectual disability (ID). The key objectives are to clarify the sensory feedback and brain mechanisms associated with motor control deficits...
This Project Grant award from the National Institute of Mental Health (NIMH), under the Mental Health Research Grants program (CFDA 93.242), provides $818,253 to The Regents of the University of California, San Francisco (UCSF) for a longitudinal study over 5 years. The study aims to evaluate the association of depression severity, cognition, and motor frailty with abnormalities in the neuromodulatory system, which controls the brain's activity state and behavioral responses. The research will...
This Project Grant award from the National Institute of Mental Health (NIMH) under CFDA 93.242 - Mental Health Research Grants provides $2,694,945 in funding to the Lieber Institute for Brain Development to conduct research on understanding the cellular and circuit function of human-induced pluripotent stem cell (hiPSC) models in relation to the complex and heterogeneous genetic risk factors and clinical/cognitive phenotypes of schizophrenia. The research aims to: 1) replicate and expand on...
This Project Grant award from the National Institute of Mental Health (NIMH), under the Mental Health Research Grants program (CFDA 93.242), provides $659,217 to develop a novel microelectrode sensor to continuously measure endogenous neuropeptide Y (NPY) release in brain tissue and single cells. The primary objective is to enhance detection of NPY, a key neuropeptide implicated in neurological disorders, by optimizing an existing NPY biosensor to improve sensitivity and selectivity while...