This Project Grant award from the National Heart, Lung, and Blood Institute (NHLBI), under the Cardiovascular Diseases Research program (CFDA 93.837), supports research by Dr. Jasleen Minhas at the University of Pennsylvania to study physical activity patterns and their association with clinical outcomes in pulmonary arterial hypertension (PAH) patients. The $364,879 award covers a 5-year period from July 1, 2024 to June 30, 2029. The key products and services to be delivered under this grant include:
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Identifying predominant patterns of heart rate and physical activity in PAH patients using advanced statistical methods on continuously-monitored data from biosensor devices.
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Integrating cardiopulmonary and physical activity measures to phenotype PAH patients and determine associations between these phenotypes and clinical outcomes.
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Assessing PAH patients' attitudes and preferences towards activity-based interventions through qualitative research methods.
This research aims to advance understanding of PAH patients' daily physical activity patterns and their relationship to disease progression, with the goal of informing the development of personalized, activity-focused interventions to improve patient outcomes.
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