This Project Grant award from the National Institute on Aging (NIA), under the Aging Research federal grant program (CFDA 93.866), will support the University of Michigan's efforts to optimize antiseizure medication deprescribing decisions across the lifespan. The $196,395 grant will be used to collect preliminary data for a future large, multi-center randomized controlled trial focused on integrating seizure risk prediction and patient preferences to guide personalized deprescribing decisions. Key objectives include defining how patient preferences influencing antiseizure medication decisions change across the lifespan, improving post-deprescribing seizure risk prediction, and refining the trial protocol for the future study. This work aims to provide more personalized, evidence-based recommendations for tailoring antiseizure medication deprescribing to an individual's risk profile, healthcare preferences, and life stage.
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