Project Grant K08DK143343
- The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), through its Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), awarded a $350,000 Project Grant to Katharos, Inc. on Jun 20, 2025. The grant supports the development of a novel extracorporeal technology, the "Phosfilter" device, which aims to enhance phosphate removal from the blood of hemodialysis patients and reduce the incidence of high phosphate-associated morbidity and...
- This federal Project Grant award of $984,000.00 was provided by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847). The objective of this study is to test a novel treatment, sodium glucose co-transporter-2 inhibitor medications, for prevention of recurrent idiopathic calcium phosphate kidney stones. This research aims to develop new prevention strategies to lower the high...
- This federal Project Grant award of $3,010,432 from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), is funding research to develop mitoprotective therapies for the treatment of acute kidney injury (AKI). The key objectives of this research are to characterize a novel mitochondrial protein target, phospholipid scramblase 3 (PLSCR3), and evaluate pharmacological activators...
- This Project Grant award of $830,500.00 from the National Institute of Diabetes and Digestive and Kidney Diseases (CFDA 93.847 Diabetes, Digestive, and Kidney Diseases Extramural Research program) supports research investigating the role of glycosphingolipids in kidney disease associated with diabetes and obesity. The key objectives are to: Test whether inhibiting glucosylceramide synthesis in podocytes, renal tubules, or the immune system can prevent progression of kidney disease in mouse...
- This $151,069 Project Grant awarded by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), aims to investigate how sex, glomerular filtration rate, and permeability impact endocytic uptake along the kidney proximal tubule. The research project, running from August 1, 2025 to July 31, 2030, will develop a multiscale model to characterize sex-based differences in glomerular...
- This $243,750 Project Grant was awarded on September 5, 2025 by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), part of the National Institutes of Health, under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847). The grant supports research to investigate the role of the protein DCLK1 in regulating the DNA damage response in proximal tubule cells, which are important mediators of chronic kidney disease (CKD). The research aims...
- This $2,967,657 Project Grant was awarded on September 1, 2025 by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847). The grant supports research by Mayo Clinic Jacksonville to investigate the role of urinary urate in regulating water balance and inhibiting cyst formation in autosomal dominant polycystic kidney disease (ADPKD). Key objectives include evaluating the impact of...
- This $128,286 Project Grant award, provided by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), will support research into the mechanisms of renal lipotoxicity and its contribution to the development of chronic kidney disease (CKD). The principal investigator will investigate the protective role of the FAF2 gene knockout in mitigating palmitate-induced lipotoxicity in...
- This federal Project Grant award of $799,952 was provided by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847). The award supports research at Northwestern University to investigate the role of the transcription factor HNF4A in the progression of chronic kidney disease (CKD) and associated complications such as inflammation, anemia, and bone/mineral disorders. The research aims...
- This $171,639 Project Grant award was provided by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847). The award supports a "Multi-omic Investigation of Uremic Toxin Sources and Accumulation in Children with Kidney Failure" conducted by the Children's Hospital of Philadelphia (CHOP). The key objectives of this research project are to: 1) Characterize the contributions...
This $166,740 Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (CFDA 93.847 - Diabetes, Digestive, and Kidney Diseases Extramural Research) aims to conduct research on the role of urinary phosphate in the progression of chronic kidney disease (CKD). The key activities under this 5-year award include: This research seeks to advance understanding of the pathophysiology of CKD progression and explore potential interventions to slow disease progression, which is an important public health goal given the high prevalence and health impacts of CKD.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $166.7k | 7/30/25 |