The National Institute of Dental and Craniofacial Research (NIDCR), through the Oral Diseases and Disorders Research program (CFDA 93.121), awarded a $959,035 project grant to the ADA Forsyth Institute, Inc. (The Forsyth Institute) to develop hydrolysis-resistant, multifunctional dental resin materials that surpass the performance and lifespan of existing methacrylate-based composites. The project aims to formulate new hybrid resin networks, incorporate antimicrobial and protein-repellent...
The National Institute of Dental and Craniofacial Research (NIDCR) awarded a $2,539,292 project grant under the Oral Diseases and Disorders Research federal grant program (CFDA 93.121) to the ADA Forsyth Institute, Inc. (The Forsyth Institute) to develop a novel operational platform and suite of multifunctional dental restoration materials. The key products and services to be delivered include: Creating a self-improving, universal dental adhesive that enhances its bond to tooth structure through...
This federal Project Grant award of $322,000.00 from the National Institute of Dental and Craniofacial Research (NIDCR) under the Oral Diseases and Disorders Research (CFDA 93.121) program supports a research project titled "Improving the Design and Implementation of School-Based Oral Health Programs Using Secondary Data Analysis". The key objectives of the project are to: 1) Explore the longitudinal caries arrest capabilities of silver diamine fluoride (SDF) applied in a...
This Project Grant award of $408,375 from the National Institute of Dental and Craniofacial Research (NIDCR), under the Oral Diseases and Disorders Research program (CFDA 93.121), will fund research on a novel biomimetic nitric oxide and hydroxyapatite (NO-HA) duo for advanced direct pulp capping. The research aims to develop a synergistic solution that can enhance bioactive and physical-mechanical barrier functions to support pulp-dentin repair and preserve tooth vitality. Key objectives...
This Project Grant award from the National Institute of Dental and Craniofacial Research (NIDCR), under the federal Oral Diseases and Disorders Research program (CFDA 93.121), provides $135,000 to the ADA Forsyth Institute, Inc. (The Forsyth Institute) to support the Forsyth Student Scholars (FSS) summer internship program. The program aims to increase the representation of underrepresented and educationally disadvantaged students in oral health research by providing high school students from...
The National Institute of Dental and Craniofacial Research (NIDCR) awarded a $157,500 Project Grant under the Oral Diseases and Disorders Research program (CFDA 93.121) to The Ohio State University to conduct research on the cellular mechanisms regulating tooth development. The research aims to determine how the signaling molecule SEMA7A influences the mineralization of dentin, elongation of tooth roots, and innervation of teeth. The study will use global and conditional SEMA7A knockout mouse...
The National Institute of Dental and Craniofacial Research (NIDCR) awarded a $441,500 Project Grant (CFDA 93.121 Oral Diseases and Disorders Research) to the University of Colorado-Denver to develop uniquely high conversion and mechanically robust composite restorative materials for improved dental applications. The award aims to investigate the structure-property relationships and mechanisms that enable these novel polymer composites to achieve exceptional strength, toughness, and wear...
This Project Grant award from the National Institute of Dental and Craniofacial Research (NIDCR), under the Oral Diseases and Disorders Research (CFDA 93.121) program, provides $1,849,232.90 to The General Hospital Corporation (doing business as Massachusetts General Hospital) to identify the cellular and molecular identity of genes and pathways defining dental mesenchymal cell differentiation and fate early in tooth development. The goal is to harness this information to develop potential...
This $433,125 Project Grant awarded by the National Institute of Dental and Craniofacial Research (NIDCR), under the Oral Diseases and Disorders Research (CFDA 93.121) program, will fund research to investigate the potential biological factors underlying the association between adverse childhood experiences (ACEs) and dental caries in children. The study aims to examine the relationships among ACEs, the oral microbiome, dental caries, and salivary stress and immunological biomarkers in children....
This Project Grant award from the National Institute of Dental and Craniofacial Research (NIDCR), under the Oral Diseases and Disorders Research program (CFDA 93.121), provides $315,000 to The Ohio State University to conduct research on how aging affects the dentin-pulp complex in teeth. The key objectives are to: 1) Identify secreted bioactive proteins in dentin that change with age, and 2) Analyze age-dependent changes in teeth. This will involve extracting molars from young and old...