This $255,769 Project Grant award from the National Cancer Institute's Cancer Research Manpower program (CFDA 93.398) will support Dr. Rozalyn Rodwin, an Assistant Professor of Pediatric Hematology-Oncology at Yale University, in developing a novel screening instrument to detect chemotherapy-induced peripheral neuropathy (CIPN) in young children aged 1-5 years. The overarching goal is to improve early identification of CIPN, a debilitating side effect impacting up to 87% of children during cancer treatment. The project will involve qualitative research to develop a proxy-report symptom-based survey that a parent or guardian can complete, followed by prospective evaluation of the survey's psychometric properties and collection of preliminary data to inform future implementation. This instrument aims to enable early detection and intervention for CIPN, which can have lifelong impacts on a child's health and development. The award will provide Dr. Rodwin with advanced training in qualitative research, survey development, and implementation science, equipping her to independently conduct future studies on screening and early intervention for treatment-related toxicities in childhood cancer survivors.
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