The National Cancer Institute (NCI) awarded a $178,541 Project Grant under the Cancer Research Manpower (CFDA 93.398) program to Oregon Health & Science University (OHSU) to establish the Experimental Therapeutics in Cancer (ETC) Training Program. This two-year postdoctoral program will train 9 PhD and MD scientists in translational oncology research, with the goal of accelerating the development of innovative cancer therapies. Trainees will participate in preclinical research projects...
The National Cancer Institute (NCI) awarded a $256,487 Project Grant under the Cancer Research Manpower (CFDA 93.398) federal grant program to the Sloan-Kettering Institute for Cancer Research. The grant funds a 5-year research project aimed at improving risk stratification and clinical management of non-small cell lung cancer (NSCLC) by developing multimodal predictive models incorporating real-world data from circulating tumor DNA sequencing, radiomics, tumor genomics, and electronic health...
The federal Project Grant award from the National Cancer Institute (NCI) provides $159,803 over a period of 5 years (9/3/2024 - 8/31/2029) to support the "INTEGRATIVE MULTIOMICS AND CLINICAL LABORATORY TRANSLATION FOR ADVANCED, RARE, AND PEDIATRIC CANCERS" project. The award aims to incorporate emerging genomic, transcriptomic, epigenomic and proteomic technologies to analyze advanced, rare, and pediatric cancers, and translate the results into clinically actionable information through...
This $160,761.51 Project Grant award from the National Cancer Institute's Cancer Research Manpower program (CFDA 93.398) supports research conducted by Oregon Health & Science University (OHSU) to investigate the molecular mechanisms controlling the MYC super-enhancer complex in FLT3-ITD acute myeloid leukemia (AML). The research aims to define the transcription factor regulators of the MYC super-enhancer and identify critical enhancer modules that could be targeted through combined...
This $2,282,687 federal Project Grant award from the National Cancer Institute (CFDA 93.393 - Cancer Cause and Prevention Research) aims to understand how various forms of integration (structural, functional, normative, interpersonal, and process) in oncology care delivery are associated with quality and outcomes. The research will examine integration across different healthcare settings, including health systems, independent oncology practices, post-acute/hospice care, and specialty pharmacies....
The National Cancer Institute (NCI) awarded a $315,143 Project Grant (CFDA 93.398 Cancer Research Manpower) to The Ohio State University for the period of September 4, 2024 through August 31, 2029. The grant will fund research activities focused on developing a better understanding of cancer biology, immunology, genetics, and translational medicine. The Ohio State University, a prominent public research institution, will serve as the prime awardee and conduct the research at its facilities in...
This National Cancer Institute Project Grant under CFDA 93.394 "Cancer Detection and Diagnosis Research" will develop and validate a multi-stage, multi-modal biomarker to predict the risk of progression from oral premalignant lesions (OPLs) to oral cavity squamous cell carcinoma (OSCC). The project, titled "PROSPECT: Premalignant Oral Lesions Pathology and Epigenetic Risk Prediction Tool," will use a combination of cytology, histology, and epigenomics to create a risk...
The National Cancer Institute (NCI) awarded a $244,048 Project Grant under the Cancer Research Manpower (CFDA 93.398) program to The Leland Stanford Junior University. The grant, awarded on September 1, 2024, will support a research project titled "High-Throughput Measurements of RNA-Mediated Regulation of Gene Expression and Oncogenesis." The project aims to systematically identify functional effector domains within human RNA-binding proteins (RBPs) and understand how dysregulation of...
The National Cancer Institute (NCI) awarded a $169,344 Project Grant under the Cancer Research Manpower (CFDA 93.398) program to the Fred Hutchinson Cancer Center in Seattle, WA. The grant titled "USING SINGLE-CELL AND SPATIAL MULTI-OMICS TO IMPROVE ADOPTIVE CELL THERAPY AGAINST PANCREATIC CANCER" aims to use advanced multi-omics technologies to gain a comprehensive understanding of how adoptive T cell therapy becomes dysfunctional within the pancreatic tumor microenvironment. The goal...
The federal Project Grant award, provided by the National Cancer Institute (NCI) under the Cancer Detection and Diagnosis Research program (CFDA 93.394), is focused on developing noninvasive imaging and blood-based biomarkers to improve prediction of immunotherapy response and clinical outcomes for patients with advanced non-small cell lung cancer (NSCLC). The $1,820,020 award, which runs from May 2024 to April 2029, will support research to: (1) create knowledge-guided radiomics and deep...