Project Grant K08AR084614
- This federal Project Grant award from the Defense Health Agency under the Military Medical Research and Development program (CFDA 12.420) provides $442,750.00 to the University of California, Davis to determine the role of histone lactylation in post-traumatic osteoarthritis and arthritic pain. The award has a performance period from February 1, 2025 to January 31, 2027 and supports advanced biomedical research aimed at transforming healthcare for military service members, veterans, and the...
- This Project Grant award of $169,344 was provided by the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846). The award supports research at the University of California, Davis to investigate the role of inflammation and immunomodulation in fracture healing in the context of polytrauma. The key objectives are to: (1) characterize the upregulation of inflammatory cytokines and innate...
- The National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) awarded a $703,634 Project Grant under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846) to The Regents of the University of California, San Francisco (UCSF). The grant, awarded on August 15, 2025, will fund a study to develop and validate age-relative measures of biochemical intervertebral disc health. The research aims to discover the age-course of biochemical disc composition,...
- The National Institute on Aging (NIA), under the Aging Research federal grant program (CFDA 93.866), awarded a $166,488 Project Grant to the University of California, Davis to investigate the role of hypoxia-inducible factor-2a (HIF-2a) signaling in age-induced bone loss. The project aims to identify mechanisms underlying bone deterioration with aging and develop novel therapies to reverse age-related osteoporotic bone loss and improve fracture resistance. The project period runs from December...
- The University of Rochester was awarded a $464,315 Project Grant from the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), under the Arthritis, Musculoskeletal and Skin Diseases Research federal grant program (CFDA 93.846). The purpose of this 5-year project, beginning on July 1, 2025, is to investigate the role of the L-type Ca2+ channel Cav1.2 in the development of Achilles tendinopathy. The research aims to identify early mediators in tendons in response to...
- The University of Southern California (USC) received a $628,174 Project Grant award from the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) under the Arthritis, Musculoskeletal and Skin Diseases Research federal grant program (CFDA 93.846). The purpose of this multi-year grant, with an ultimate completion date of March 31, 2030, is to support research into the cellular origins and molecular mechanisms underlying the development of arthrofibrosis, a debilitating...
- The National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) awarded a $600,475 Project Grant on March 24, 2025 to the University of California, Davis (UC Davis) to engineer the fetal environment for in utero treatment of spina bifida bone defects. The research project, which runs through January 31, 2030, aims to leverage the regenerative capacity of the fetal environment and endogenous stem cells to regenerate bony vertebrae defects and protect the repaired spinal cord,...
- This Project Grant award of $1,801,179.00 from the Defense Health Agency's Military Medical Research and Development program (CFDA 12.420) supports advanced biomedical research at the University of California, Davis (UC Davis) focused on the "Contribution of Bone Mass and Fracture to Bone Metastasis in Prostate Cancer". The research aims to transform healthcare for military service members, veterans, and the broader public by investigating innovative medical solutions to address...
- The Defense Health Agency awarded a $2,401,711.00 Project Grant on August 15, 2023 to The Regents of the University of California, San Francisco (UCSF) under the Military Medical Research and Development program (CFDA 12.420). The grant supports a 4-year research project focused on "JOINT SHAPE CHANGE AS A TARGET FOR THE UNDERSTANDING, DIAGNOSIS, PREVENTION, AND TREATMENT OF OSTEOARTHRITIS." As a sub-award under this grant, Sutter Bay Hospitals' California Pacific Medical Center...
- The federal Project Grant award of $649,391 provided by the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846) is supporting research to enhance healing after injury. The overarching objective is to define the mechanisms that restrain tissue regeneration in order to develop new therapeutics to improve healing of the gut and skin following injury or infection. The 5-year project, which...
The University of California, Davis (UC Davis) was awarded a 4-year, $170,316 Project Grant from the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) on August 10, 2025. The grant supports research focused on developing methods to mitigate the formation of trauma-induced heterotopic ossification (THO), an extremely painful condition caused by aberrant bone formation in severely injured soft tissues. The research aims to target neuroinflammation, a key driver of THO initiation, by leveraging expertise in peripheral nerve surgery and regenerative medicine. The grant will allow the Principal Investigator, a board-certified plastic surgeon, to expand his research capabilities in areas of inflammation and THO under the mentorship of experts in these domains. The overarching goal is to establish the candidate as an impactful researcher in this critical field and advance understanding of potential therapeutic approaches to prevent this debilitating condition.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $170.3k | 7/30/25 |