Project Grant K08AI185310
Award Date
8/20/24
Completion Date
7/31/29
Dollars Obligated
$186K
Federal Agency
National Institute of Allergy and Infectious Diseases
Federal Grant Program
93.855
Assistance Type
Project Grant
Place of Performance
Nashville, TN 37203, USA
Similar Awards
This Project Grant award of $312,000 from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855) will support research to develop a single-cell resolution understanding of pathogenesis and antibiotic tolerance in Staphylococcus aureus. The key objectives are to: 1) Explore the relationship between heterogeneous transcriptional responses to the antibiotic vancomycin and tolerance to this drug, and 2) Investigate...
The National Institute of Allergy and Infectious Diseases (NIAID) awarded a $189,558 Project Grant to Duke University to conduct research on the genomic determinants of antibiotic treatment failure in Staphylococcus aureus bacteremia (SAB). The research, funded under CFDA 93.855 - Allergy and Infectious Diseases Research, aims to identify bacterial genotypes associated with SAB antibiotic treatment failure using in vivo murine models and bacterial genome-wide association studies. The goal is...
This federal Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID), under the Allergy and Infectious Diseases Research program (CFDA 93.855), will provide $2,683,302.00 to Vanderbilt University Medical Center (VUMC) over a 5-year period from July 1, 2024 to May 31, 2029. The funding will support research focused on understanding how hyperglycemia and diabetes impact the severity of Staphylococcus aureus infections. The project aims to determine the mechanisms...
This Project Grant award, totaling $231,700.00, was awarded on January 24, 2025 by the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855). The grant aims to develop biologic therapeutics capable of blocking the agglutination of Staphylococcus aureus (S. aureus) bacteria, a leading cause of complicated infections including sepsis, septic arthritis, and endocarditis. The research team at Texas A&M University...
This federal Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID), under the Allergy and Infectious Diseases Research program (CFDA 93.855), provides $749,417 to support research focused on developing novel bactericidal antibiotics to address the growing problem of multi-drug resistant pathogens. The research team at Harvard University aims to synthesize and evaluate new antibiotic candidates that target the lipoprotein transport pathway in Gram-negative...
The National Institute of Allergy and Infectious Diseases (NIAID) awarded a $212,169 Project Grant under the Allergy and Infectious Diseases Research program (CFDA 93.855) to The Johns Hopkins University to advance mentorship and research in antimicrobial resistance (AMR). The grant supports the awardee's efforts to expand their knowledge of molecular mechanisms of antibiotic resistance, incorporate new research techniques into their lab, and provide mentorship to trainees conducting both...
The National Institute of Allergy and Infectious Diseases (NIAID), under the Allergy and Infectious Diseases Research program (CFDA 93.855), awarded a $294,824 Project Grant to the University of Massachusetts Medical School (UMass Medical) to investigate the use of glutamine starvation as a means to enhance antibiotic efficacy against Mycobacterium tuberculosis (MTB), a major public health threat responsible for nearly 2 million deaths annually. The project aims to understand the mechanistic...
This Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID), under the Allergy and Infectious Diseases Research program (CFDA 93.855), provides $226,253 to The Washington University in St. Louis, Missouri to support research focused on understanding how the host protein ADAM10 modulates interactions between neutrophils and the endothelium in the context of Staphylococcus aureus infection. The research aims to generate a spatiotemporal analysis of these...
This federal Project Grant award, valued at $637,275.00 and awarded by the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), supports research to uncover the mechanisms by which Gram-negative bacterial pathogens develop rapid tolerance to chemical stressors, such as antibiotics. The research aims to elucidate how these bacteria can inhibit the functioning of existing porin proteins in their outer membranes...
This Project Grant award, with a total funding amount of $267,310, was provided by the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855). The grant aims to evaluate the role of a lipoic acid transfer protein, LipL, in Staphylococcus aureus metabolism and virulence. The key objectives are to determine how LipL interfaces with the phosphotransacetylase, Pta, to control energy balance during overflow metabolism,...