Project Grant K01HL175212
- This Project Grant award from the National Heart, Lung, and Blood Institute (NHLBI), under the Federal Grant Program for Cardiovascular Diseases Research (CFDA 93.837), provides $123,104 to Emory University to conduct research on factors contributing to cardiovascular disease (CVD) comorbidities in persons living with HIV (PWH). The key objectives are to: 1) assess relationships between the metabolome, lipidome, HIV reservoir, and subclinical CVD, analyzing differences by sex; and 2) determine...
- This federal Project Grant award for $170,601, provided by the National Heart, Lung, and Blood Institute (CFDA 93.837 Cardiovascular Diseases Research), supports the development and pilot testing of a multi-component remote care intervention for rural patients living with heart failure. The project aims to: 1) elicit feedback on remote intervention strategies to inform implementation of heart failure care within rural communities; 2) conduct a pilot trial to examine the feasibility and...
- This Project Grant award from the National Heart Lung and Blood Institute, under the Cardiovascular Diseases Research federal grant program (CFDA 93.837), provides $186,408 to the University of Washington to develop robust models that identify patients at high risk for persistent hypoxemic respiratory failure (HRF). The goal is to improve the ability to distinguish patients with persistent HRF early, which is critical for enrolling the highest-risk patients in clinical trials for new HRF...
- This Project Grant award from the National Heart, Lung, and Blood Institute (CFDA 93.837 Cardiovascular Diseases Research) provides $232,498 to Emory University to develop a natural language processing and machine learning model to analyze electronic health records and predict risk of Fontan failure in patients with single ventricle heart defects. The goal is to improve detection of multi-organ complications in this population and define physiologic phenotypes to enable more targeted treatment...
- This Project Grant award from the National Heart, Lung, and Blood Institute (CFDA 93.837 Cardiovascular Diseases Research) to Vanderbilt University Medical Center (VUMC) provides $173,352 to conduct research on the molecular characterization of frailty and functional limitations in heart failure with preserved ejection fraction (HFpEF). The key objectives are to measure associations between the human proteome and measures of multi-organ function in HFpEF, and to identify and prioritize...
- This Project Grant award from the National Heart, Lung, and Blood Institute (CFDA 93.837 Cardiovascular Diseases Research) is funding research to discover novel biomarkers and biological mechanisms underlying early-stage heart failure (HF). The $147,486 award to Duke University will support the development of an automated computational phenotype to identify early-stage HF, which will then be applied to large population cohorts. The research aims to leverage multi-omics data integration and...
- This federal Project Grant award of $169,344 from the National Heart Lung and Blood Institute (CFDA 93.837 Cardiovascular Diseases Research) aims to advance the management of critically ill adults with non-ARDS acute hypoxemic respiratory failure (NAHRF). The key objectives are to: 1) Develop clinical prediction models for mortality in NAHRF patients; 2) Apply machine learning to detect NAHRF subphenotypes associated with differential clinical outcomes; and 3) Use sequencing-based whole...
- This Project Grant award from the National Heart Lung and Blood Institute (CFDA 93.837 Cardiovascular Diseases Research) aims to study the effects of structural racism on disparities in environmental exposures and cardiovascular disease (CVD) outcomes. The $123,368 award to The Research Foundation For The State University Of New York (UEI LVVEB3CF8MB8), effective September 16, 2025 through August 31, 2030, will leverage New York's all-payer hospital database and integrate it with primary data...
- This federal Project Grant award of $110,635.00 from the National Heart Lung and Blood Institute (CFDA 93.837 - Cardiovascular Diseases Research) aims to characterize how red blood cell aggregation and membrane deformability affect endothelial cell injury and microvascular thrombosis in sepsis patients. The project will use microfluidics assays to analyze patient blood samples and apply machine learning to determine the impact of rheology on clinical outcomes. The research will also assess the...
- This Project Grant award from the National Heart, Lung, and Blood Institute (CFDA 93.837 Cardiovascular Diseases Research) provides $224,142 to conduct an epidemiologic study on the prevalence and correlates of atherosclerotic resilience among 4,000 participants in the NHLBI-funded RURAL cohort study across the Southeastern U.S. The study aims to determine the prevalence of coronary artery calcium (CAC) scores of zero, a marker of atherosclerotic resilience, according to age, sex, and race in...
This Project Grant award of $142,870 from the National Heart Lung and Blood Institute (CFDA 93.837 - Cardiovascular Diseases Research) supports Emory University's investigation into the multi-level determinants of inequities in end-of-life care for adults with heart failure. The key objectives are to: Characterize the influence of individual and hospital-level factors on end-of-life heart failure care through hierarchical multiple regression analysis. Quantify the impact of neighborhood-based attributes on end-of-life heart failure care using geographically bounded areas in hierarchical multiple regression. Explore end-of-life heart failure needs and perceived care opportunities through semi-structured interviews with patients, caregivers, and clinicians. The study aims to develop interventions that address disparities in heart failure end-of-life outcomes through practice and policy changes. This 4-year grant, awarded on September 1, 2025, supports Dr. Cross's career development in mixed methods research, advanced health outcomes analytics, and designing socio-behavioral interventions.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $142.9k | 9/1/25 |