Project Grant K01DA063751
- This Project Grant award from the National Institute of Environmental Health Sciences (CFDA 93.879 - Medical Library Assistance) is providing $3,484,662.00 to Cedars-Sinai Medical Center to conduct research on using artificial intelligence (AI) methods for large-scale epidemiological studies. The research will focus on leveraging patient reports of medication adherence and tolerability to gain novel insights into intentional medication non-adherence, which is a significant public health...
- This federal Project Grant award of $767,506 from the National Institute on Drug Abuse (NIDA) under the Drug Use and Addiction Research Programs (CFDA 93.279) aims to leverage integrative modeling and AI-based tools to develop safer opioid painkillers. The project focuses on understanding how low-efficacy opioid receptor (MOR) agonists activate MOR-mediated G protein pathways differently from high-efficacy opioid drugs, in order to inform the design of safer opioid therapeutics. The award...
- This $325,734 Project Grant award from the National Institute on Drug Abuse (NIDA), under the Drug Use and Addiction Research Programs (CFDA 93.279), will fund the development, evaluation, and dissemination of "STATWISEAI" - an AI-powered educational tool to enhance methodological rigor in analyzing complex, large-scale datasets for biomedical and behavioral research. The key products and services to be delivered through this 3-year award (9/15/2025 - 8/31/2028) include: 1)...
- This federal Project Grant award of $798,828.00 from the National Institute on Drug Abuse (NIDA) under the Drug Use and Addiction Research Programs (CFDA 93.279) aims to discover novel small molecule therapeutics for the safe and effective treatment of opioid use disorder (OUD). The key products and services to be delivered include: The development of an AI platform called M3.AI that will integrate target-based and phenotype-based methodologies to efficiently identify new drug candidates for OUD...
- This Project Grant award from the National Institute on Drug Abuse (NIDA), under the CFDA program "Drug Use and Addiction Research Programs" (93.279), will support research to uncover the neurophysiological signatures within the addiction circuitry related to acute opioid use. The $159,711 award, effective January 1, 2025 through December 31, 2029, will leverage a unique ability to directly record local field potentials from awake humans with implanted brain electrodes. This will...
- The National Institute on Drug Abuse (NIDA), under the Drug Use and Addiction Research Programs (CFDA 93.279), awarded a $397,829 Project Grant to Callentis Consulting Group LLC, a woman-owned small business in Austin, Texas. The grant, awarded on May 1, 2025, supports the development of an artificial intelligence (AI) platform to discover new therapeutics for substance use disorders. The key products and services to be delivered include: 1) Curated training datasets and machine learning...
- This federal Project Grant award, titled "Dynamic Treatment Regimes for Personalized Opioid Use Disorder Care," was provided by the National Institute on Drug Abuse (NIDA) under the Drug Use and Addiction Research Programs (CFDA 93.279). The $199,800 award supports the research efforts of Dr. Jason Brian Gibbons, an Assistant Professor at the University of Colorado Anschutz Medical Campus, over a 5-year period from August 2025 to July 2030. The overarching objective of the project is...
- This $304,215 Project Grant award from the National Institute on Drug Abuse (NIDA), under the Drug Use and Addiction Research Programs (CFDA 93.279), supports the development and validation of a novel software platform for decentralized clinical trials in substance use disorder (SUD) research. The software will incorporate large language models to address challenges in SUD clinical trials, such as participant diversity, recruitment, and retention. The award recipient, Carina Medical LLC, is a...
- The National Institute on Drug Abuse (NIDA), under the Drug Use and Addiction Research Programs (CFDA 93.279), has awarded a $306,872 Project Grant to Biomotivate LLC to develop and evaluate the PEACE Platform, a novel solution that leverages personalized audiovisual content and machine learning algorithms to help individuals with opioid use disorders (OUDs) build their capacity to manage negative emotions and stressors. The research design involves integrating generative AI, predictive...
- This federal Project Grant award from the National Institute on Drug Abuse (NIDA), under the Drug Use and Addiction Research Programs (CFDA 93.279), is intended to develop and evaluate an adaptive psychological intervention to improve pain management and reduce opioid use following an injury. The $264,995 grant, awarded on September 15, 2025, will fund the optimization and feasibility testing of a two-part intervention. The first part is a 15-minute computerized brief intervention focused on...
This Project Grant award from the National Institute on Drug Abuse (NIDA), under the Drug Use and Addiction Research Programs (CFDA 93.279), provides $191,700.00 to Cedars-Sinai Medical Center to develop and validate an AI-driven framework to efficiently predict and identify severe opioid adverse drug effects, including persistent use and related post-surgical outcomes, from electronic health record (EHR) data. The project aims to leverage automated machine learning, knowledge graphs, and generative AI to enhance data cleaning and feature engineering processes, addressing limitations of traditional data processing methods. The research will use EHR records of over 6,000 elective spinal fusion patients, with the potential to expand to external and publicly available datasets. The award period is from August 1, 2025 to July 31, 2030.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $191.7k | 7/29/25 |