Project Grant HT9425261E028
- Federal Grant Award Summary The Cleveland Clinic Foundation received a $1.28 million Project Grant from the Defense Health Agency (DHA) under the Military Medical Research and Development program (CFDA 12.420) effective September 1, 2025, through August 31, 2029. This four-year research award supports investigation of the biological mechanisms and therapeutic relevance of the SLC1A1 amino acid transporter in kidney cancer. The research will be conducted at the Cleveland Clinic Foundation's...
- Federal Grant Award Summary The Cleveland Clinic Foundation received a $559,992 Project Grant from the Defense Health Agency (DHA) under the Military Medical Research and Development program (CFDA 12.420) to support bench-to-bedside development of superior CAR T-cell (chimeric antigen receptor T-cell) therapy for leukemia. The award period runs from September 30, 2025, through September 29, 2028. This research initiative aims to translate laboratory discoveries into clinical applications that...
- Federal Grant Award Summary The Cleveland Clinic Foundation received a $799,998 Project Grant award from the Defense Health Agency (DHA) under the Military Medical Research and Development program (CFDA 12.420) effective September 15, 2025, through September 14, 2028. The grant supports research focused on "Strategies Enhancing Spinal Plasticity to Promote Recovery from Spinal Cord Injury," with work to be performed at the organization's Cleveland, Ohio location. This research...
- Federal Project Grant Award Summary The Cleveland Clinic Foundation received a $999,566 Project Grant from the Defense Health Agency under the Military Medical Research and Development program (CFDA 12.420), awarded November 1, 2025, with a completion date of October 31, 2028. The award supports research titled "Magnetic Resonance Imaging-Guided Transcriptomic Analysis of Spinal Cord Neurodegeneration and Demyelination in Multiple Sclerosis," to be conducted at the organization's...
- This federal Project Grant award of $1,200,000 from the Defense Health Agency's Military Medical Research and Development program (CFDA 12.420) to The Cleveland Clinic Foundation supports research to develop therapeutic strategies to disrupt the CX26-FAK-NANOG complex in order to attenuate cancer stem cell self-renewal and triple-negative breast cancer progression. The research aims to transform healthcare for military service members, veterans, and the broader public by investigating innovative...
- This Project Grant award of $471,000.00 was provided by the Defense Health Agency under the Military Medical Research and Development program (CFDA 12.420). The funding supports research by The Cleveland Clinic Foundation to develop next-generation prostate cancer therapeutics by exploiting the allosteric regulation of the androgen receptor. The award period is from September 1, 2023 to August 31, 2025. As a prime recipient of federal grants, The Cleveland Clinic Foundation has a history of...
- The U.S. Department of Defense's Defense Health Agency (DHA) awarded a $2,602,024 Project Grant to The Cleveland Clinic Foundation under the Military Medical Research and Development (CFDA 12.420) federal grant program. The grant, awarded on September 30, 2024, will fund research on the "Role of Stress in the Degradation of Intestinal IgA and Intestinal Health" over a 4-year period ending on September 29, 2028. As a prominent academic medical center, The Cleveland Clinic Foundation...
- This federal Project Grant award, provided by the Defense Health Agency under the Military Medical Research and Development program (CFDA 12.420), is funding advanced biomedical research conducted by The Cleveland Clinic Foundation to investigate a novel mechanism for disrupting ovarian cancer progression. The total award amount is $780,357.00, with a performance period from May 1, 2025 to April 30, 2029. The research aims to elucidate the nuclear localization of the complement regulator CD55 as...
- Federal Project Grant Award Summary The Defense Health Agency (DHA) awarded $352,000 under the Military Medical Research and Development program (CFDA 12.420) to the Sloan-Kettering Institute for Cancer Research for the project period September 1, 2025, through August 31, 2027. The award supports research focused on augmenting the in vivo efficacy of a novel lanosterol synthase inhibitor in glioblastoma treatment. This research aligns with the DHA's mission to transform healthcare for service...
- The Defense Health Agency awarded a $640,000 Project Grant under the Military Medical Research and Development program (CFDA 12.420) to The Cleveland Clinic Foundation, a non-profit academic medical center, to conduct research focused on "Evolutionary Experimentation Highlights Novel Therapeutic Vulnerabilities in Endometrial Cancer." The award duration is from September 1, 2024 to August 31, 2026. The Cleveland Clinic Foundation, which has extensive experience as both a prime...
The Cleveland Clinic Foundation received a $750,000 Project Grant from the Defense Health Agency (DHA) under the Military Medical Research and Development program (CFDA 12.420) for the period of April 1, 2026 through March 31, 2029. The award supports research investigating focal adhesion dependencies in CDH1-deficient lobular breast cancers, with performance occurring at the Cleveland Clinic Health System facility in Cleveland, Ohio. This research initiative aligns with the DHA's broader mission to advance biomedical research that transforms healthcare for military service members, veterans, and the general public through innovative investigations into cancer biology and therapeutic mechanisms. The project delivers basic and applied biomedical research focused on understanding the molecular dependencies and vulnerabilities specific to lobular breast cancers with CDH1 deficiency. This research contributes to the Military Medical Research and Development program's strategic objectives of developing novel diagnostic tools and therapeutic interventions to address critical health challenges. As a leading academic medical center with substantial experience in federal biomedical research funding, Cleveland Clinic Foundation brings specialized oncology research capabilities and clinical expertise to advance the scientific understanding of breast cancer biology with potential applications for military-relevant populations and the broader public health sector.Federal Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $750.0k | 3/12/26 |