Project Grant HT9425261E005
- Federal Project Grant Award Summary The University of Texas Health Science Center at San Antonio received a $1.57M Project Grant from the Defense Health Agency (DHA) under the Military Medical Research and Development program (CFDA 12.420) for the period September 1, 2025 through August 31, 2029. The grant supports research focused on targeting METTL3 (methyltransferase-like 3) to overcome drug resistance in metastatic clear cell renal cell carcinoma. This four-year initiative represents the...
- Federal Grant Award Summary The University of Texas Southwestern Medical Center received a $1.65 million Project Grant from the Defense Health Agency (DHA) under the Military Medical Research and Development program (CFDA 12.420) for a three-year period commencing April 1, 2026 and concluding March 31, 2029. The grant supports research aimed at targeting CDK4/6 inhibitor resistance in patients with estrogen receptor-positive (ER+) breast cancer, a clinically significant challenge in oncology...
- Federal Grant Award Summary The University of Texas Southwestern Medical Center received a $1.476 million Project Grant from the Defense Health Agency (DHA) under the Military Medical Research and Development program (CFDA 12.420), awarded on August 15, 2025, with a completion date of August 14, 2028. This award supports the development and research of an in situ tumor vaccine designed to stimulate antitumor immunity against breast cancer. The three-year project will be conducted at UT...
- Federal Grant Award Summary The University of Texas Health Science Center at San Antonio received a $1.56M Project Grant award from the Defense Health Agency (DHA) under the Military Medical Research and Development program (CFDA 12.420), effective September 30, 2025, through September 29, 2029. The award supports a randomized clinical trial designed to reduce aggression in military personnel. As a comprehensive academic medical center with established expertise in serving military and veteran...
- Federal Grant Award Summary The University of Texas Southwestern Medical Center received a $1,311,922 Project Grant from the Defense Health Agency under the Military Medical Research and Development program (CFDA 12.420) effective September 1, 2025, through August 31, 2028. The award funds research and development activities focused on next-generation renal cell carcinoma (RCC) mouse models designed to reproduce human oncogenotypes and advance therapeutic development. This research initiative...
- Federal Project Grant Award Summary The University of Texas Health Science Center at Houston (UTHealth) received a $544,892 Project Grant from the Defense Health Agency under the Military Medical Research and Development program (CFDA 12.420), effective August 1, 2025, through July 31, 2028. The award supports research and development of a novel peptide-drug conjugate designed for precision-targeted DNA damage in neuroendocrine tumors. This three-year research initiative represents UTHealth's...
- Summary of Federal Grant Award The University of Texas Southwestern Medical Center (UT Southwestern) received a $1.23 million Project Grant from the Defense Health Agency (DHA) under the Military Medical Research and Development program (CFDA 12.420) for a four-year period beginning August 1, 2025 and concluding July 31, 2029. The award supports research focused on "Imaging Strategies and Biomarkers for Detecting the Metabolic Interplay of Glutamine and Aspartate in Renal Cell Carcinoma...
- Federal Project Grant Award Summary The University of Texas Southwestern Medical Center received a $319,800 Project Grant award from the Defense Health Agency (DHA) under the Military Medical Research and Development program (CFDA 12.420) effective November 1, 2025, through October 31, 2028. The award supports research focused on novel hypoxia-inducible factor 2 (HIF-2) regulators and therapeutic targets for kidney cancer treatment. This research initiative aligns with the DHA's mission to...
- Federal Project Grant Award Summary The University of Texas Health Science Center at Houston received a $154,084 Project Grant award from the Defense Health Agency under the Military Medical Research and Development program (CFDA 12.420) for the period August 1, 2025 through July 31, 2026. The award supports research exploring aberrant alternative cleavage and polyadenylation linked to RB1 mutations in osteosarcoma development. This research initiative contributes to the Defense Health...
- Federal Grant Award Summary The University of Texas MD Anderson Cancer Center received a $1.43M Project Grant from the Defense Health Agency (DHA) under the Military Medical Research and Development program (CFDA 12.420) for the period October 1, 2025 through September 30, 2028. The award supports research focused on building T-cell products for neurofibromatosis type 1 (NF1)-associated malignant peripheral nerve sheath tumors (MPNST) through antigen discovery and epigenome targeting. This...
The University of Texas Health Science Center at San Antonio received a $750,000 Project Grant from the Defense Health Agency (DHA) under the Military Medical Research and Development program (CFDA 12.420), effective March 1, 2026 through February 28, 2029. The award supports research targeting KDM1A/LSD1 (lysine-specific demethylase 1) to overcome radiation resistance in triple-negative breast cancer brain metastases. This three-year initiative addresses a critical clinical challenge in oncology by investigating mechanisms of radiation resistance in an aggressive breast cancer subtype that commonly metastasizes to the brain, with the goal of developing therapeutic approaches that enhance treatment efficacy for military service members and the broader patient population. As a comprehensive academic medical center with substantial experience in biomedical research and clinical translation, UTHSCSA is well-positioned to execute this translational cancer research project. The research will be conducted at the institution's San Antonio, Texas campus, where investigators will leverage institutional expertise in cancer biology, radiation oncology, and therapeutic development. Deliverables under this award are expected to include mechanistic findings regarding KDM1A/LSD1 function in radiation resistance, preclinical data supporting novel therapeutic strategies, and potentially translational pathways toward clinical application in treating brain metastases from triple-negative breast cancer.Federal Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $750.0k | 2/26/26 |