This Project Grant award in the amount of $590,625.00 was provided by the Defense Health Agency (DHA) under the Military Medical Research and Development (CFDA 12.420) federal grant program. The grant supports a pilot study at the University of California, Los Angeles (UCLA) to investigate dual immunotherapy (PD1/CD73) in combination with chemotherapy for patients with pancreatic adenocarcinoma, with a focus on understanding the immune mechanisms of resistance. The award period runs from...
This Project Grant award of $405,000.00 from the Defense Health Agency's Military Medical Research and Development program (CFDA 12.420) supports research by Panorama Research Incorporated, a for-profit biotech company in Sunnyvale, California. The award aims to develop novel immunotherapies that target dual cancer-specific antigens for the treatment of advanced ovarian cancer. The research project will utilize a safe and controlled immune booster to enhance the efficacy of these targeted...
This Project Grant award of $519,854.00 from the Department of Defense's Military Medical Research and Development program (CFDA 12.420) supports intravital imaging research of melanoma tumors at the University of California Irvine. The goal is to discover mechanisms and improve patient surveillance after checkpoint blockade immunotherapy. The award, with a start date of September 15, 2023 and completion date of September 14, 2026, will fund research to transform healthcare for Service Members...
This federal Project Grant award of $188,403 from the Defense Health Agency's Military Medical Research and Development program (CFDA 12.420) supports research at the University of California, Los Angeles (UCLA) to develop new cell-mediated immunotherapeutic strategies for small-cell lung cancer. The award, effective from January 1, 2025 to December 31, 2025, will fund advanced biomedical research initiatives at UCLA targeting innovative treatments for this form of lung cancer. The Military...
The Defense Health Agency awarded a $828,591 Project Grant under CFDA 12.420, the Military Medical Research and Development program, to Duke University. The grant supports research titled "Targeting the Tumor Microenvironment to Enhance Immunotherapy for SCLC", with a performance period from May 1, 2025 to April 30, 2027. This research aims to transform healthcare for military service members, veterans, and the public by advancing innovative biomedical investigations focused on...
This federal Project Grant award of $610,059.00 from the Defense Health Agency's Military Medical Research and Development program (CFDA 12.420) supports research by The Johns Hopkins University to investigate "The Aging Microenvironment as a Driver of Pancreatic Cancer Metastasis." The award has a performance period from July 1, 2025 to June 30, 2028 and aims to transform healthcare for military service members, veterans, and the general public through innovative biomedical...
This $835,531 Project Grant awarded by the Defense Health Agency under the Military Medical Research and Development (CFDA 12.420) program will fund a research project at The Johns Hopkins University to develop a pooled mutant KRAS-targeted long peptide vaccine combined with anti-PD-1 and anti-CTLA-4 antibodies for patients with stage IV mismatch repair-proficient (MMR-P) pancreatic ductal adenocarcinoma. The project aims to transform healthcare for military service members and the broader...
The Department of Defense's Defense Health Agency awarded a $558,832 Project Grant to Tufts University School of Medicine under the Military Medical Research and Development program (CFDA 12.420) on September 30, 2024. This grant will support research focused on "Targeting Differentiation Epitope in CD11b of Tumor-Associated Inflammatory Monocytes: A Novel Adjuvant Dendritic Cell Therapy Approach for Mucosal Melanoma." The research aims to develop an innovative dendritic cell-based...
The Defense Health Agency awarded a $602,814 Project Grant to the University of Nebraska Medical Center (UNMC) under the Military Medical Research and Development program (CFDA 12.420). The grant, with a performance period from November 1, 2024 to October 31, 2027, supports research to investigate "Targeting Extracellular Nucleoside Metabolism as a Strategy to Potentiate the Effects of Immunotherapy in Pancreatic Ductal Adenocarcinoma." The project aims to explore innovative approaches...
The Trustees of the University of Pennsylvania were awarded a $560,870 Project Grant from the Department of the Army Medical Command under the Military Medical Research and Development program. The grant will fund research from September 2021 through September 2024 to target hepatocyte-derived factors in order to improve the efficacy of immunotherapy for pancreatic cancer. The Military Medical Research and Development program supports basic, applied, and advanced biomedical research with the...