This federal Project Grant award from the Department of the Army Medical Command, under the Military Medical Research and Development program (CFDA 12.420), provides $665,655.00 to The University of Kentucky Research Foundation to conduct research on "LEVERAGING PRECLINICAL REPEATED BLAST TRAUMATIC BRAIN INJURY TO MODEL MILITARY-RELEVANT POST-TRAUMATIC EPILEPSY". The project aims to advance the understanding and treatment of post-traumatic epilepsy, a condition of particular...
This Project Grant award, with a total funding amount of $999,965.00, was provided by the Department of the Army Medical Command under the Military Medical Research and Development (CFDA 12.420) federal grant program. The award is supporting research conducted by Yale University to investigate the role of the TDP-43 protein in the development of trauma-associated Alzheimer's disease related dementia. The project aims to elucidate the protein dynamics of TDP-43 and its potential contribution to...
This federal Project Grant award from the National Institute on Aging (CFDA 93.866 - Aging Research) provides $423,500 to The University of Kentucky Research Foundation to examine the role of the transforming growth factor-activated kinase 1 (TAK1) in tau pathology following repetitive mild traumatic brain injuries (TBIs). The research aims to determine an optimal dosage and treatment regimen of the small molecule therapeutic BNC-1 that can reduce TAK1 phosphorylation and subsequent tau...
The Project Grant award, titled "PROGRAM TO CHARACTERIZE EVOLVING ENDOPHENOTYPES OF DEGENERATION AFTER TRAUMATIC BRAIN INJURY (PROCEED-TBI)", was provided by the Defense Health Agency for $7,956,997.00 with a period of performance from September 30, 2023 to September 29, 2027. The grant supports biomedical research related to the Military Medical Research and Development program (CFDA 12.420), with a focus on characterizing clinically relevant animal models of traumatic brain injury...
This $489,065 Project Grant was awarded by the Defense Health Agency on July 1, 2025 under the Military Medical Research and Development (CFDA 12.420) federal grant program. The award funds research at the University of North Carolina at Chapel Hill (UNC-CH) to develop "Potentiated Chip Variants as Therapeutics to Alleviate Tau Pathology and Neurodegeneration". The research aims to explore innovative approaches to preventing, diagnosing, and treating neurodegenerative conditions,...
The federal Project Grant award of $860,998.00 was issued by the Defense Health Agency (DHA) under the Military Medical Research and Development (CFDA 12.420) federal grant program. The award, with a performance period from April 1, 2025 to March 31, 2028, supports neurophysiology research focused on understanding the epileptogenesis signals and biomarkers underlying post-traumatic epilepsy. This research, conducted by the Regents of the University of California, San Francisco (UCSF), aims to...
The Department of the Army Medical Command awarded a $745,381 Project Grant to The University of Kentucky Research Foundation under the Military Medical Research and Development (CFDA 12.420) federal grant program. The grant, awarded on May 1, 2025, supports research to enhance the therapeutic potential of nanoparticle-mediated immunotherapeutics for spinal trauma, with a performance period through April 30, 2028. As a non-profit research organization, the University of Kentucky Research...
This Project Grant award from the Defense Health Agency under the Military Medical Research and Development program (CFDA 12.420) is supporting research into the role of SUMO conjugation in Alzheimer's disease-related impairment of synaptic function and memory following traumatic brain injury (TBI). The $750,000 award to The Trustees of Columbia University in the City of New York will fund a collaborative project with researchers at the University of Toronto and Istituto di Ricerche...
The Defense Health Agency awarded a $749,905 Project Grant to The Roskamp Institute Inc. under the Military Medical Research and Development federal grant program (CFDA 12.420). The grant will fund research from September 2023 through September 2026 to investigate microglial NOX2/NLRP3 inflammasome activation and its role in driving tau pathology and cognitive impairments in chronic traumatic brain injury. Specifically, the Roskamp Institute will conduct basic, applied, and advanced biomedical...
The U.S. Defense Health Agency awarded a $817,200 Project Grant under the Military Medical Research and Development program (CFDA 12.420) to The Roskamp Institute, Inc. in Sarasota, Florida. The grant, awarded on September 1, 2024, will support a 3-year research project titled "Targeting APOE Bioenergetics for Reducing the Risk of Neurodegeneration After Chronic Traumatic Brain Injury." The research aims to investigate mitochondrial bioenergetics, tau protein pathology,...