This federal Project Grant award for $802,500.00 was provided by the Defense Health Agency under the Military Medical Research and Development (CFDA 12.420) program. The award will fund preclinical gene therapy studies in a mouse model of TSC2 at Baylor College of Medicine in Houston, TX over the period of May 1, 2025 to April 30, 2028. The research aims to transform healthcare for military service members and the broader public by exploring innovative approaches to disease prevention,...
This federal Project Grant award of $1,442,061.00, awarded on April 1, 2024 by the Defense Health Agency, supports research under the Military Medical Research and Development program (CFDA 12.420) to investigate the role of podocyte ceramide synthase 6 in focal segmental glomerulosclerosis (FSGS). The primary awardee, the University of Texas Health Science Center at San Antonio, will conduct basic, translational, and clinical research to determine how genetic and toxin-induced FSGS affects...
The federal Project Grant award, totaling $1,683,194.00, was provided by the Defense Health Agency under the Military Medical Research and Development (CFDA 12.420) program. The grant supports research at Brigham & Women's Hospital Inc., a renowned academic medical center and research institution, to investigate the role of the glycome in TSC biomarker identification and molecular pathogenesis. The research aims to advance the understanding of Tuberous Sclerosis Complex (TSC), a rare genetic...
The federal Project Grant award ID HT94252410749, valued at $793,572.00 and awarded on August 15, 2024 by the Defense Health Agency, supports a novel translational research project focused on understanding the pathophysiology of tuberous sclerosis complex (TSC). The project will be conducted by Brigham & Women's Hospital Inc., a prominent academic medical center and research institution affiliated with Harvard Medical School and part of the Mass General Brigham healthcare system. This...
The University of Maryland, Baltimore received a $1,383,874 Project Grant award from the Defense Health Agency under the Military Medical Research and Development (CFDA 12.420) federal grant program. The grant supports a 4-year research project titled "Deciphering the Tripartite Intramolecular Regulatory Mechanism of Polycystin 1 Implicated in Polycystic Kidney Disease." The research aims to advance the understanding of the molecular mechanisms underlying polycystic kidney disease, a...
This $1,206,372 federal Project Grant award from the Defense Health Agency under the Military Medical Research and Development (CFDA 12.420) program is funding research at the University of Michigan to study the role of primary cilia alterations in the pathogenesis and treatment of systemic sclerosis. The award, which began on April 15, 2025 and runs through April 14, 2029, supports advanced biomedical research initiatives focused on transforming healthcare for military service members and the...
This federal Project Grant award of $110,000.00 from the Defense Health Agency under the Military Medical Research and Development program (CFDA 12.420) supports research by University College Dublin (UCD) to investigate the role of the unfolded protein response in clear cell renal cell carcinoma, with the goal of developing novel therapeutic strategies for this disease. The project will be conducted over a one-year period from September 1, 2024 to August 31, 2025. The Military Medical...
This federal Project Grant award, valued at $1,312,000.00 and awarded by the Defense Health Agency under the Military Medical Research and Development (CFDA 12.420) program, supports research efforts by the Regents of the University of California, San Francisco (UCSF) to upregulate and image Nectin4 in order to enhance Nectin4-targeted therapies for bladder cancer. The 4-year award, with a performance period from August 1, 2025 to July 31, 2029, will enable UCSF researchers to investigate...
The University of Cincinnati received a $243,000 Project Grant award from the Department of the Army Medical Command under the Military Medical Research and Development program (CFDA 12.420) to conduct research on "Characterization of Novel Perivascular Lesions Caused by Specific Deletion of TSC2 in Hematopoietic Cells." The award period is from May 1, 2024 to April 30, 2026. The Military Medical Research and Development program supports biomedical research aimed at improving the...
This $309,528 Project Grant was awarded by the Defense Health Agency on February 1, 2024 under the Military Medical Research and Development program (CFDA 12.420) to the University of Kansas Medical Center Research Institute, Inc. (KUMCRI). The grant supports a project titled "Evaluating the Role of Somatic Mutations in Autosomal Dominant Polycystic Kidney Disease Using Single-Cell Genomics", which aims to advance scientific understanding and treatment of this condition through...