This federal Project Grant award of $799,999.00 was provided by the Defense Health Agency under the Military Medical Research and Development (CFDA 12.420) program. The award supports the "RESUSCITATION BY ENDOTHELIAL STABILIZATION AND TARGETED OXYGEN RESCUE (RESTOR) PLATFORM FOR VASCULARIZED COMPOSITE ALLOTRANSPLANTATION" research project at Wake Forest University Health Sciences (WFUHS), a leading academic medical center and research institution. The goal of this project is to...
This federal Project Grant award of $499,999.00 from the Defense Health Agency under the Military Medical Research and Development program (CFDA 12.420) is supporting research conducted by the University of Pittsburgh on nontoxic immunosuppression for vascularized composite allotransplantation (VCA) using vitamin D3 analogues. The research will explore innovative approaches to prevent rejection and improve outcomes for VCA procedures, which are critical for service members and others requiring...
This $380,785 Project Grant was awarded by the Defense Health Agency under the Military Medical Research and Development program (CFDA 12.420) to the University of Pittsburgh. The award provides funding for a 3-year research project titled "MICROPARTICLE DELIVERY OF CHEMOKINE MUTEINS GUIDING CHEMOKINE RECEPTOR ENGINEERED TREG FOR TOLERANCE INDUCTION AFTER VASCULAR COMPOSITE ALLOGRAFT TRANSPLANT." The project aims to develop a microparticle-based delivery system to administer...
This $653,317 Project Grant award from the Defense Health Agency's Military Medical Research and Development program (CFDA 12.420) supports the development of a novel graft-localized drug delivery platform at Wake Forest University Health Sciences (WFUHS). The funding will be used to conduct research aimed at attenuating innate inflammation and optimizing immunosuppression in vascularized composite allotransplantation over a 2-year period from September 2024 to September 2026. WFUHS, a leading...
This $2.29 million Project Grant from the Department of the Army Medical Command's Military Medical Research and Development program (CFDA 12.420) supports research into the "Regulation of ALK1 Signaling in the Endothelium" from September 1, 2021 through August 31, 2025. The University of Pittsburgh will conduct the research as the primary awardee. A $200,000 subaward to the University of Massachusetts Medical School will support related research activities. Through this funding, the...
The University of Pittsburgh has been awarded a $540,800 Project Grant from the Department of Defense's Military Medical Research and Development program (CFDA 12.420) to conduct research on microparticle delivery of chemokine muteins guiding chemokine receptor engineered Treg for tolerance induction after vascular composite allograft transplant. The 3-year award, which runs from September 15, 2024 to September 14, 2027, will support innovative scientific studies aimed at developing novel...
This $305,917 federal Project Grant awarded by the Defense Health Agency under the Military Medical Research and Development program (CFDA 12.420) supports the development of an off-the-shelf reparative T regulatory cell (Treg) immunotherapy to limit tissue damage and initiate effective repair and resolution after lung injuries. The University of Pittsburgh, a major research institution, is the prime awardee on this 2-year grant with a performance period from December 1, 2023 to November 30,...
The U.S. Defense Health Agency has awarded a $499,998 Project Grant to the University of Colorado-Denver under the Military Medical Research and Development (CFDA 12.420) federal grant program. The grant, with a performance period from November 1, 2024 to October 31, 2026, is for developing a preservation method for vascularized composite allotransplantation (VCA) during static cold storage. This research aims to transform healthcare for military service members and the broader public by...
This federal Project Grant award of $1,572,933.00 was provided by the Defense Health Agency under the Military Medical Research and Development (CFDA 12.420) program. The grant supports advanced biomedical research to transform healthcare for military service members and the broader public, with a focus on exploring innovative approaches to disease prevention, diagnosis, treatment, and management across multiple medical disciplines. The University of Pittsburgh, a major public research...
The U.S. Department of Defense's Defense Health Agency (DHA) awarded a $750,000 Project Grant to Stanford University to implement a spatial and single-cell multiplexed platform for the development of targeted therapies for vascularized composite allotransplantation. The funding is provided through the Military Medical Research and Development (CFDA 12.420) federal grant program, which supports advanced biomedical research to transform healthcare for military service members and the broader...