The Department of Defense, through the Military Medical Research and Development program (CFDA 12.420), awarded a $1,273,300 Project Grant to The Children's Hospital of Philadelphia (CHOP) to conduct research on identifying and reversing functional cerebellar circuit dysfunctions in a mouse model of Friedreich's ataxia. The grant, with a performance period from September 1, 2024 to August 31, 2028, will support CHOP's pioneering research efforts to advance understanding and treatment of this...
The Children's Hospital of Philadelphia (CHOP) has been awarded a $1,773,720.00 Project Grant under the Military Medical Research and Development program (CFDA 12.420) by the Defense Health Agency. This award, with a period of performance from July 1, 2024 to June 30, 2028, will support research to elucidate the cardiomyopathy associated with the mitochondrial disorder Friedreich's ataxia. CHOP, a leading pediatric hospital and research facility, will leverage its expertise in areas like genetic...
The Children's Hospital of Philadelphia (CHOP) was awarded a $801,000 Project Grant from the Defense Health Agency under the Military Medical Research and Development program (CFDA 12.420). The grant supports research targeting "MARROW NICHE DYSREGULATION DURING STEM CELL TRANSPLANT FOR BONE MARROW FAILURE ASSOCIATED WITH MONOSOMY 7 MYELODYSPLASTIC SYNDROMES." This multi-year research project, running from September 1, 2023 to August 31, 2026, aims to investigate medical solutions...
This federal Project Grant award from the Defense Health Agency, under the Military Medical Research and Development program (CFDA 12.420), provides $1,366,365.00 to The Children's Hospital of Philadelphia (CHOP) to conduct a research study titled "BRAIN CHARTS IN CHILDREN AND ADOLESCENTS WITH NEUROFIBROMATOSIS TYPE 1". The study aims to advance healthcare for children by improving the understanding of brain development in those with neurofibromatosis type 1, a genetic disorder that...
This federal Project Grant award from the Department of the Army Medical Command under the Military Medical Research and Development program (CFDA 12.420) provides $356,000.00 to The Children's Hospital of Philadelphia (CHOP) to study the impact on ketosis phenotype. The performance period for this award is from Sep 1, 2024 to Aug 31, 2026. As a leading pediatric research institution, CHOP leverages its expertise in areas such as genetic disorders and neurological conditions to contribute to...
This $152,761 federal Project Grant award from the Department of Defense's Military Medical Research and Development program (CFDA 12.420) supports a research study at The Children's Hospital of Philadelphia (CHOP) investigating the use of quantitative sodium magnetic resonance imaging (MRI) and chemical exchange saturation transfer (CEST) to analyze low-grade gliomas in children with neurofibromatosis type 1. The 2-year study, which commenced on September 15, 2023, aims to advance diagnostic...
The U.S. Department of Defense, through the Military Medical Research and Development program (CFDA 12.420), awarded a $356,000 Project Grant to The Children's Hospital of Philadelphia (CHOP) to conduct research on "INTERROGATING CELL DEATH MECHANISMS AND IDENTIFYING THERAPEUTIC LEADS IN ZERBRAFISH AND HUMAN CELL SURF1 MODELS OF LEIGH SYNDROME." The research project aims to advance understanding of the cell death mechanisms involved in Leigh syndrome, a rare neurological disorder,...
This Project Grant award from the Defense Health Agency under the Military Medical Research and Development program (CFDA 12.420) provides $676,117 to The Children's Hospital of Philadelphia Research Institute to conduct research on expanded GAA-GGA chimeric repeats in Friedreich ataxia. The research aims to transform healthcare for military service members, veterans, and the broader public by advancing innovative biomedical research to address critical health challenges. The award period runs...
This $356,000 Project Grant award from the Defense Health Agency under the Military Medical Research and Development program (CFDA 12.420) supports the development of a novel gene therapy for mitochondrial complex I deficiency at the Children's Hospital of Philadelphia (CHOP). The award period runs from March 1, 2024 to February 28, 2026. CHOP, a leading pediatric hospital and research institution, will leverage its expertise in areas like rare genetic disorders to advance this innovative...
The Department of Defense's Military Medical Research and Development (CFDA 12.420) program has awarded a $1,746,810 Project Grant to The Children's Hospital of Philadelphia to conduct research on "Combination Therapy for High-Risk, MYCN-Amplified Neuroblastoma". The award period runs from July 1, 2025 to June 30, 2028. The research aims to transform healthcare for military service members, veterans, and the broader public by investigating innovative medical solutions to address...