This federal Project Grant award of $1,995,027.00 from the Defense Health Agency under the Military Medical Research and Development program (CFDA 12.420) supports research conducted by the University of California, San Diego (UCSD) to develop therapy for C9ALS (chromosome 9 open reading frame 72-associated amyotrophic lateral sclerosis) using engineered RNA-targeting zinc finger proteins. The award, effective June 1, 2025 through May 31, 2028, will fund UCSD's specialized medical research and...
This federal Project Grant award, with an ID of HT94252510188, was provided by the Defense Health Agency (DHA) under the Military Medical Research and Development (CFDA 12.420) program. The $1,181,251 grant, awarded on April 15, 2025, supports the University of California, Los Angeles (UCLA) in conducting research on "Neuronal Exosome-Based Biomarkers for ALS Diagnosis and Disease Progression." The project aims to develop novel biomarkers derived from neuronal exosomes to enhance the...
The University of California, San Diego received a $694,650 Project Grant award from the Department of the Army Medical Command under the Military Medical Research and Development federal grant program (CFDA 12.420). The two-year award will support research on RNA-directed therapy for amyotrophic lateral sclerosis (ALS) linked to the C9ORF72 gene using engineered zinc finger nucleases. The Military Medical Research and Development program aims to transform military and public health through...
The Department of the Army Medical Command awarded a $1,180,437 Project Grant to the University of California, Los Angeles (UCLA) under the Military Medical Research and Development program (CFDA 12.420). The grant supports UCLA's research to evaluate circulating cell-free DNA as a biomarker for diagnosing and tracking the progression of amyotrophic lateral sclerosis (ALS). The award began on March 1, 2024 and is scheduled for completion by February 28, 2026. Through this Project Grant, UCLA...
This federal Project Grant award, with a total funding amount of $1,078,882, was issued by the Defense Health Agency under the Military Medical Research and Development program (CFDA 12.420). The grant supports advanced biomedical research focused on understanding the multimodal therapeutic actions of neural stem cells in amyotrophic lateral sclerosis (ALS). Key elements of the research scope include: developing a chemical engineering approach to ALS, investigating surgical intervention...
The University of California, San Diego will receive $790,000 under a two-year Project Grant award from the Department of the Army Medical Command. The grant is part of the Military Medical Research and Development program administered by the agency under Catalog of Federal Domestic Assistance number 12.420. The university will conduct research on neuron-targeted caveolin gene therapy as a potential route of administration to treat amyotrophic lateral sclerosis. Specifically, the funding will...
The federal Project Grant award in the amount of $925,757.00, awarded by the Defense Health Agency under the Military Medical Research and Development (CFDA 12.420) program, supports research at Wake Forest University Health Sciences (WFUHS) to selectively reduce repeat expansion RNA with small molecules to treat C9ORF72 mediated amyotrophic lateral sclerosis (ALS). The award, with a period of performance from April 1, 2025 to March 31, 2027, will enable WFUHS, a private non-profit academic...
The federal Project Grant award, titled "TARGETING AXONAL REGENERATION PATHWAYS AS A THERAPEUTIC APPROACH TO ALS", was granted to the University of Miami by the Defense Health Agency under the Military Medical Research and Development (CFDA 12.420) program. The $894,330 award, which began on February 1, 2025 and is scheduled for completion on January 31, 2027, supports advanced biomedical research initiatives focused on transforming healthcare for military service members and the...
The Regents of the University of California, San Francisco (UCSF) has been awarded a $499,985 Project Grant from the Defense Health Agency under the Military Medical Research and Development program (CFDA 12.420). The grant will fund a 2-year research project titled "DIET, EXERCISE, AND INFLAMMATION IN EARLY-STAGE NEURONAL ALPHA-SYNUCLEIN DISEASE" to investigate novel approaches for treating neurodegenerative disorders relevant to military personnel and the broader population. As a...
The University of California, San Diego (UCSD) was awarded a $2,179,391 Project Grant from the Defense Health Agency under the Military Medical Research and Development program (CFDA 12.420) to conduct proof-of-concept preclinical studies and GMP development of AAV-SynCav1 gene technology to treat amyotrophic lateral sclerosis (ALS). The award, which began on May 1, 2024, will support research and development efforts aimed at advancing a novel gene therapy approach to address this debilitating...