This $724,500.00 Project Grant was awarded by the Defense Health Agency under the Military Medical Research and Development program (CFDA 12.420) to Duke University on March 1, 2025. The award will fund research to investigate "Targeting Dormancy-Associated Immune Tolerance to Eliminate Residual Breast Cancer" over a performance period extending to February 29, 2028. As a leading research institution, Duke University will leverage its extensive capabilities in medical research to...
The Department of Defense's Defense Health Agency awarded a $4,818,759 Project Grant to Duke University under the Military Medical Research and Development program (CFDA 12.420) for the project "SINGLE-CELL AND SPATIAL ANALYSIS OF LETHAL BREAST CANCERS". The grant, awarded on April 1, 2024, will fund research to improve understanding and treatment of lethal breast cancers through advanced single-cell and spatial analysis techniques. This work supports the program's goals of...
The Defense Health Agency awarded Duke University a $3,811,150.00 Project Grant under the Military Medical Research and Development program (CFDA 12.420) to conduct a research project titled "SINGLE-CELL AND SPATIAL ANALYSIS OF LETHAL BREAST CANCERS". The grant period runs from April 1, 2024 to March 31, 2028. The key products and services to be delivered under this award include comprehensive single-cell and spatial analysis of breast cancer samples to characterize tumor heterogeneity...
The Defense Health Agency awarded Duke University a $1,167,250 Project Grant (CFDA 12.420 - Military Medical Research and Development) with a performance period from June 1, 2024 to May 31, 2027. The grant funding supports Duke's research on the role of the NLRP3-NLRC5 signaling pathway in melanoma immune evasion and dormancy. The research aims to advance the understanding of mechanisms underlying melanoma progression, with the potential to inform new therapeutic approaches. As a prominent...
Duke University was awarded a $931,969 project grant from the Defense Health Agency under the Military Medical Research and Development program (CFDA 12.420). The grant will fund research from July 1, 2023 to June 30, 2026 to develop epigenetic signatures to predict pathological nodal stage for de-escalation of axillary surgery in patients with clinically node-positive breast cancer. The research aims to transform patient care by investigating medical solutions that could help reduce the need...
The Department of Defense's Defense Health Agency awarded Duke University a $1,344,946 Project Grant on September 1, 2023 through the Military Medical Research and Development program (CFDA 12.420). This grant supports a 3-year research project titled "Understanding Heterogeneity and Improving the Precision of Prostate Cancer Clinical Outcomes in the Modern Era." The research aims to advance understanding and treatment of prostate cancer, with a focus on improving clinical outcomes for...
The Department of Defense's Defense Health Agency awarded a $1,182,931 Project Grant to Duke University on February 1, 2024 under the Military Medical Research and Development program (CFDA 12.420). The grant supports a 3-year project focused on "NK CELL RESPONSE AS A CLINICAL DIFFERENTIATOR OF ENDOCRINE THERAPIES" that will be conducted at Duke University's Office of Research Administration Division. This research aims to improve understanding of the clinical implications of natural...
This $161,000 federal Project Grant was awarded by the Defense Health Agency on April 1, 2025 under the Military Medical Research and Development (CFDA 12.420) program. The grant supports research conducted by Duke University focused on "Breast Cancer Brain Metastases: Integrating Immunogenomic and Phenotypic Vulnerabilities to Improve Outcomes." The research aims to investigate innovative approaches to the prevention, diagnosis, and treatment of breast cancer brain metastases, with...
The Defense Health Agency awarded Duke University a $402,500 Project Grant under the Military Medical Research and Development program (CFDA 12.420) for the period of June 1, 2023 through May 31, 2025. The grant will support Duke University's research efforts to target the ferropotosis protection mechanism of serum to disable cancer metastasis. The Military Medical Research and Development program aims to transform military and public health through innovative medical research solutions for both...
The Defense Health Agency awarded a $784,602 Project Grant to Dana-Farber Cancer Institute, Inc. (doing business as Dfci) under the Military Medical Research and Development program (CFDA 12.420). The grant will support research from January 2023 to January 2026 to develop next-generation immunotherapy for breast cancer by turning breast cancer cells against themselves. The Military Medical Research and Development program aims to transform military and public health through innovative medical...