Project Grant HT94252310722
- The U.S. Defense Health Agency's Military Medical Research and Development program (CFDA 12.420) awarded a $199,908 Project Grant to the Institut National De La Sante Et De La Recherche Medicale (Inserm) to model hemangioblastomas using induced pluripotent stem cells carrying mutations in the von Hippel-Lindau gene. This 2-year project, scheduled for completion by April 30, 2026, aims to transform healthcare for Service Members and the American public through innovative biomedical research. As a...
- The Institute For Cancer Research has been awarded a $940,000 Project Grant from the Defense Health Agency under the Military Medical Research and Development program (CFDA 12.420) to conduct a mouse model study of epigenetic events in melanomagenesis. This 3-year grant, with a period of performance from July 1, 2024 to June 30, 2027, will enable the non-profit research organization to investigate the underlying epigenetic mechanisms driving the development of melanoma. As a prime grantee, The...
- The Department of Defense's Defense Health Agency awarded a $820,833 Project Grant to The Schepens Eye Research Institute, Inc., a non-profit research organization affiliated with Harvard Medical School and Massachusetts Eye and Ear. The grant, funded through the Military Medical Research and Development program (CFDA 12.420), supports a research project to "Identify the Liver Microenvironment that Drives Uveal Melanoma Metastasis and Immunity." The 3-year award, effective from...
- The U.S. Defense Health Agency awarded Yale University a $912,487 Project Grant under the Department of Defense's Military Medical Research and Development program (CFDA 12.420) to conduct research on the role of Polycomb Repressive Complex 1 in the progression of uveal melanoma. The 3-year research project, starting on September 15, 2023 and ending on September 14, 2026, aims to advance the understanding of this specific protein complex's involvement in the development and spread of a rare form...
- The Institute For Cancer Research, a non-profit research organization and subsidiary of Temple University, was awarded a $534,445 Project Grant from the Defense Health Agency under the Military Medical Research and Development program (CFDA 12.420). The grant supports research to investigate NETRIN G1 ligand as a new immunomodulatory target and early biomarker in pancreatic cancer, with a project period from August 1, 2023 to July 31, 2026. The Institute For Cancer Research has extensive...
- The U.S. Department of Defense, through the Military Medical Research and Development program (CFDA 12.420), has awarded a $947,746 Project Grant to the Dana-Farber Cancer Institute, Inc. (DFCI) to conduct research on "IDENTIFICATION OF THE LIVER MICROENVIRONMENT THAT DRIVES UVEAL MELANOMA METASTASIS AND IMMUNITY". The 3-year grant, beginning on September 1, 2024 and ending on August 31, 2027, will enable DFCI, a non-profit cancer research center in Boston, MA, to investigate the liver...
- The U.S. Department of Defense's Defense Health Agency awarded a $780,000 Project Grant to Thomas Jefferson University, doing business as Sidney Kimmel Medical College, for a 3-year research project titled "DEGRADATION OF MUTANT GNAQ 11 IN UVEAL MELANOMA CELLS". The grant is funded through the Military Medical Research and Development program (CFDA 12.420), which supports biomedical research related to military medicine, including cancer, neurological disorders, and other conditions...
- The Department of Defense, through the Military Medical Research and Development program (CFDA 12.420), awarded a $1,128,000 Project Grant to The Institute For Cancer Research to conduct research on "Restoring PALB2 Function as a Mechanism of PARP1 Resistance in BRCA1-Mutant EOC". The award, with a performance period from July 1, 2024 to June 30, 2028, supports innovative scientific research aimed at improving health outcomes for military service members, veterans, and the broader...
- The U.S. Defense Health Agency has awarded a $367,622 Project Grant under the Military Medical Research and Development program (CFDA 12.420) to St. Vincent's Institute of Medical Research, a foreign-owned non-profit organization based in Australia. The grant supports a 2-year research project focused on studying the reprogramming of mRNA translation as a driver of drug resistance in ovarian cancer. The research aims to transform healthcare for military service members and the broader public...
- The Project Grant award of $564,000 from the Defense Health Agency's Military Medical Research and Development program (CFDA 12.420) supports research by the Institute for Cancer Research (ICR) to explore the role of the MUL1 gene in prostate cancer development. The two-year project, commencing on May 1, 2025, aims to investigate the underlying mechanisms by which MUL1 may contribute to prostate tumorigenesis. As a non-profit subsidiary of Temple University, the ICR has extensive expertise in...
The Institut Curie, a foreign-owned non-profit organization in France, has been awarded a $1,907,499 Project Grant from the U.S. Defense Health Agency under the Military Medical Research and Development program (CFDA 12.420). The grant, which runs from September 30, 2023 to September 29, 2027, supports the Institut Curie's research on genetic predispositions and tumor markers for uveal melanoma, the most common eye cancer in adults. Specifically, the Institut Curie is conducting crystallization and structure determination studies on various myosin motor proteins, as well as investigating the roles of midbody-associated mRNAs in cell proliferation and differentiation. Additionally, the Institut Curie is involved in research on novel separation methods for extracellular RNA carriers and extracellular vesicle-mediated immunomodulation in HIV infection and nicotine abuse. The Institut Curie is collaborating with several U.S. universities on these research projects.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $1.9m | 8/7/23 |