The Medical College of Wisconsin, Inc. was awarded a $935,999 Project Grant from the Defense Health Agency on April 15, 2023 to complete work by April 14, 2027. The grant is part of the agency's Military Medical Research and Development program (CFDA 12.420), which supports basic, applied, and advanced biomedical research to transform military and public health care through innovative solutions for battlefield medicine and other priorities.
Specifically, this award will fund research into RBP-mediated MLO formation in chemoresistance and cancer recurrence. The grantee will investigate how RNA-binding proteins regulate the formation of multinucleated giant cancer cells and contribute to chemotherapy resistance and cancer returning after initial treatment. Insights from this work have the potential to lead to new therapeutic strategies to prevent cancer recurrence.
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