This Project Grant award of $402,500.00 from the National Institute on Deafness and Other Communication Disorders (NIDCD) under the Research Related to Deafness and Communication Disorders (CFDA 93.173) program supports research investigating the relationship between speech perceptual learning and speech production in individuals with Parkinson's disease. The award aims to use acoustic measures to determine how challenges with speech perception or learning can predict individual differences in...
This federal Project Grant award from the National Institute on Deafness and Other Communication Disorders (NIDCD), under the Research Related to Deafness and Communication Disorders federal grant program (CFDA 93.173), provides $187,297 to conduct research on speech amplification devices for individuals with Parkinson's disease (PD). The key objectives are to: 1) quantify the acoustic and perceptual effects of using speech amplification devices, with and without behavioral speech strategies,...
The federal Project Grant award of $173,140 from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, will support research to elucidate the role of neural activity in the degeneration of midbrain dopamine neurons in Parkinson's disease. The project aims to utilize novel mouse models to chronically manipulate the activity and dopamine metabolism within dopamine neurons,...
The Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) federal grant program, supports research to investigate the relationship between cortical planning activity and disordered spoken interaction. The $163,184 award, with a period of performance from May 1, 2025 to April 30, 2027, will leverage access to deep brain stimulation (DBS) electrode...
This federal Project Grant award for $142,074, awarded by the National Institute on Deafness and Other Communication Disorders (NIDCD) under CFDA Program 93.173 - Research Related to Deafness and Communication Disorders, supports research to investigate the impact of dysbiosis (imbalanced microbial composition) and immune activation on the formation of glottic scar following acute laryngeal injury. The key objectives are to: 1) Determine the effect of dysbiosis and immune activation on glottic...
This Project Grant award, funded by the National Institute on Deafness and Other Communication Disorders (NIDCD) under the Research Related to Deafness and Communication Disorders program (CFDA 93.173), aims to develop a novel biomarker for objectively measuring vocal hyperfunction in patients with voice disorders. The $1,375,744 award to New York University School of Medicine will support research to create a synchronized multi-sensor surface electromyography system to quantify coordination and...
This Project Grant award from the National Institute of Environmental Health Sciences (NIEHS) under the Environmental Health (CFDA 93.113) program provides $390,823 to the RU School of Osteopathic Medicine (RowanSOM) to conduct research on Parkinson's disease. The goal is to identify treatment-resistant components of feeding and swallowing impairments, and their neuropathological correlates, in Parkinson's disease models. The study will compare behavioral, biomechanical, and neuromuscular...
The National Institute on Aging (NIA) awarded a $167,743 Project Grant under the Aging Research federal grant program (CFDA 93.866) to The University of Iowa. This 2-year grant, running from September 2024 to August 2026, will fund research to characterize the impact of presbyphonia, a common voice disorder in older adults, on social interaction and well-being. The research team will use a combination of validated patient-reported outcome measures, voice analysis, and qualitative methods...
This federal Project Grant award, provided by the National Institute on Deafness and Other Communication Disorders (NIDCD), supports research under the Research Related to Deafness and Communication Disorders program (CFDA 93.173). The $464,268 award aims to investigate the role of dopamine and sensorimotor function in stuttering, a speech fluency disorder that affects millions of Americans. The research will use magnetoencephalography (MEG) imaging to examine indicators of speech sensorimotor...
This $406,260 federal Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program will support research to define the molecular mechanisms that contribute to neurodegeneration in Parkinson's disease (PD) and related dementias. The research aims to establish a role for alpha-synuclein-mediated membrane permeabilization in the spread of alpha-synuclein...
This federal Project Grant award from the National Institute on Deafness and Other Communication Disorders (CFDA 93.173 - Research Related to Deafness and Communication Disorders) totaling $126,442 will fund research at the University of Wisconsin-Madison to investigate vocal dysfunction and brainstem pathology in the prodromal stage of Parkinson's disease.
The key objectives of the research are to: 1) evaluate differences in vocal, swallowing, gastrointestinal, and limb motor behaviors between healthy control rats and a genetic rat model of Parkinson's disease; 2) assess pathological alpha-synuclein accumulation in brainstem regions associated with the vagus nerve and substantia nigra; and 3) identify relationships between vocal/vagal behaviors and brainstem pathology in the prodromal stage of the disease. This work aims to improve understanding of early vocal and other vagally-mediated deficits in Parkinson's disease, particularly differences between males and females, to guide future identification and treatment of these symptoms. The grant award period is from Dec 15, 2024 to Jun 30, 2025.