Project Grant F30DC021872

Award Date 6/14/24
Completion Date 12/31/27
Dollars Obligated $205K
Federal Grant Program
93.173
Assistance Type
Project Grant
Place of Performance
San Francisco, CA 94158, USA

The National Institute on Deafness and Other Communication Disorders (NIDCD) awarded a $204,592 Project Grant under the Research Related to Deafness and Communication Disorders program (CFDA 93.173) to the Regents of the University of California, San Francisco (UCSF). The purpose of this grant is to develop a bilingual speech neuroprosthesis that can restore natural and rapid communication for individuals with anarthria, or the loss of speech due to neurological conditions.

The key objectives are to: 1) Assess cortical activity patterns underlying bilingual speech production to determine if lexical access is language-specific while articulation is shared across languages, 2) Develop algorithms to decode the user's intended language and phrase content from cortical activity in bilingual participants with anarthria, and 3) Explore which cortical representations enable rapid generalization of decoding algorithms across languages. This research aims to create a speech neuroprosthesis that can provide communication restoration for any individual with paralysis, regardless of their language background. The grant period runs from June 2024 through December 2027.

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