Project Grant DP2ES039817
- The National Institute of Environmental Health Sciences awarded the President and Fellows of Harvard College $118,206 on May 5, 2026, under the Environmental Health program (CFDA 93.113) to conduct epidemiological research on prenatal environmental stressors and pediatric cancer risk. The recipient, working through Harvard T.H. Chan School of Public Health, will provide robust estimates of associations between prenatal and early-life environmental exposures and pediatric cancer incidence using...
- The National Institute of Environmental Health Sciences awarded the University of Washington $180,332 on February 21, 2026, under the Environmental Health program (CFDA 93.113) to develop large-scale, multidimensional reference databases of ToxCast compounds and their metabolites using ion mobility-mass spectrometry (IM-MS) for human exposome applications. The project addresses analytical challenges in measuring the chemical exposome—the complete array of non-genetic environmental factors...
- The National Institute of Environmental Health Sciences awarded Harvard Pilgrim Health Care, Inc. $3.796 million on April 23, 2026, under the Environmental Health program (CFDA 93.113) to examine how early-life exposure to neighborhood environmental disadvantage and nephrotoxicants—including air pollutants and metals—associates with kidney function decline and elevated blood pressure across childhood and early adulthood. The research leverages Project Viva, an ongoing longitudinal pre-birth...
- The National Institute of Environmental Health Sciences awarded $119,524 to Harvard T.H. Chan School of Public Health on July 1, 2026, under the Environmental Health program (CFDA 93.113) to investigate biological and psychosocial pathways linking early life lead exposure to later-life cognitive function and decline. The research leverages the St. Louis Baby Tooth Study cohort, which provides early-life lead exposure measurements across prenatal and early postnatal periods in a population of...
- Federal Project Grant Award Summary The National Institute of Environmental Health Sciences (NIEHS) awarded a $433,185 Project Grant (R21 exploratory grant under CFDA 93.113 – Environmental Health program) to Harvard T.H. Chan School of Public Health effective September 16, 2025, with a completion date of September 15, 2027. The award funds research investigating the associations between ambient particle radioactivity (PR) exposure and lung cancer survival outcomes, utilizing data from the...
- The National Institute of Environmental Health Sciences awarded the Trustees of Boston University $245,250 on August 13, 2026, under the Environmental Health program (CFDA 93.113) to develop and pilot an integrated air pollution exposure assessment framework for reproductive health research. The project combines real-time residential indoor monitoring with residence-level outdoor pollution models and weekly time-activity data collected across preconception and gestational periods. Aim 1...
- The National Institute of Environmental Health Sciences, part of the Department of Health and Human Services National Institutes of Health, awarded $815,546 to Icahn School of Medicine at Mount Sinai on June 22, 2026, under the Environmental Health program (CFDA 93.113) to investigate how early-life chemical exposures affect executive function and brain development across adolescence. The research leverages naturally shed deciduous teeth as biomarkers to measure in utero and early childhood...
- The National Institute of Environmental Health Sciences awarded Boston University Medical Campus $197,600 on November 1, 2025, under the Environmental Health program (CFDA 93.113) to examine early-life exposure to ferroalloy metal mixtures and adolescent cognition. The research investigates how exposure to neuroactive metals—manganese, lead, chromium, and copper—released through ferroalloy industrial emissions affects neurodevelopment in children and adolescents living near such facilities....
- The National Institute of Environmental Health Sciences awarded Michigan State University $402,066 on September 27, 2025, under the Environmental Health program (CFDA 93.113) to investigate how the epicardium and the IRE1 signaling pathway mediate the effects of environmental chemical exposure on cardiac function. The project employs three-dimensional human heart organoids derived from induced pluripotent stem cells to model the impact of per- and polyfluoroalkyl substances (PFAS) on lipid...
- The National Institute of Environmental Health Sciences awarded The Trustees of Columbia University in the City of New York $126,355 on August 4, 2026, under the Environmental Health program (CFDA 93.113) to assess tissue-specific responses to metal exposure in humans through development of a blood-based biomarker framework. The funded research establishes whether two recently developed diagnostic tools—the Organ Age Clock (OrgAnge), which uses organ-specific proteins in plasma to estimate...
The National Institute of Environmental Health Sciences awarded $722,000 to the President and Fellows of Harvard College (Harvard T.H. Chan School of Public Health) on August 26, 2026, under the Environmental Health program (CFDA 93.113) to develop an integrated molecular exposomics platform mapping how environmental chemicals move from blood to tissues and alter cellular function. The project establishes three synergistic modules. Module 1 creates comprehensive blood exposomics using high-resolution mass spectrometry-based untargeted analysis to detect over 10,000 chemical features per individual—a thousand-fold increase over conventional methods. Module 2 employs desorption electrospray ionization mass spectrometry imaging to visualize environmental chemical distributions within human tissue architecture, revealing spatial patterns of exposure. Module 3 integrates blood and tissue exposomics through methodologically consistent electrospray ionization-based platforms to quantify relationships linking systemic exposures to tissue-specific accumulation and localized pathology. Preliminary work identified hundreds of environmental chemicals differentially abundant in pre-diagnostic samples from individuals who later developed lung cancer, including novel contaminants absent from current biomonitoring panels. Performance occurs in Boston, Massachusetts, with a period of performance extending through July 31, 2031. The award is structured as a Project Grant, a standard assistance type under NIEHS's research portfolio supporting investigator-led environmental health research.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $722.0k | 8/26/26 |