Project Grant DP2AT013749
- This federal Project Grant award, funded by the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), supports research to define molecular mechanisms underlying the gut microbiome's ability to resist colonization by pathogens like Vibrio cholerae. The $2,065,745 grant, awarded to the Regents of the University of California at Riverside, aims to provide a mechanistic understanding of how the biochemical environment of...
- The University of California, Davis received a $435,769 Project Grant award from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859). This 5-year grant, awarded on September 1, 2025, supports the university's research efforts to uncover the physical principles that define the function of the cellular glycocalyx. The key objectives are to develop novel imaging tools, computational models, and genetic engineering...
- The National Institute of General Medical Sciences (NIGMS) awarded a $347,086 Project Grant under the Biomedical Research and Research Training program (CFDA 93.859) to the University of California, San Diego (UCSD) to develop "Precision, Functional Glyconanoassemblies Through Supramolecular Design." This research aims to advance the state-of-the-art in synthetic glycan assemblies by employing a coordination-driven self-assembly approach to create multivalent glycomolecules with atomic...
- The University of California, Merced received a $550,108 Project Grant award under the National Institute of General Medical Sciences' (NIGMS) Biomedical Research and Research Training program (CFDA 93.859) to conduct fundamental research on the genetic regulation of microbial community formation, with a focus on biofilms. The project, which runs from May 5, 2025 to March 31, 2030, aims to provide new insights into the molecular and mechanistic bases of biofilm development, regulation, and...
- The University of Southern California received a $342,342 Project Grant from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859) for their project titled "CHEMISTRY-ENABLED GLYCOSCIENCE." The project aims to develop and apply chemistry-enabled approaches to address unresolved questions in the field of glycoscience, which studies the role of glycans (complex carbohydrates) in biological processes and...
- The University Enterprises, Inc. (UEI) was awarded a $532,500.00 Project Grant by the U.S. Department of Health and Human Services National Institutes of Health under the Biomedical Research and Research Training program (CFDA 93.859). The project aims to examine the genetic determinants of gut microbiota function, with a focus on understanding the role of sorbitol metabolism in the commensal bacterium Paraclostridium bifermentans and its interactions with the pathogenic bacterium Clostridioides...
- This federal Project Grant award for $353,500.00, provided by the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), supports research to investigate the impact of xenobiotic exposure on the gut microbiome and its resilience against gastrointestinal pathogens. The research program aims to fill a critical knowledge gap by examining how xenobiotics and their biotransformation products affect the composition, metabolism,...
- The University of California Irvine (UC Irvine) received a $765,540 Project Grant award from the National Science Foundation (NSF) Division of Molecular and Cellular Biosciences program (CFDA 47.074) to investigate how the spatial arrangement of microbial cells affects the ecosystem process of denitrification. The research will use evolutionary algorithms and 3D printing to construct and analyze pre-defined spatial communities of bacteria capable of performing different steps of the...
- The National Institute of General Medical Sciences (NIGMS) awarded a $384,527 Project Grant under the Biomedical Research and Research Training program (CFDA 93.859) to the University of California, Irvine (UCI) for the project "Deciphering the Interactome and Functions of Disordered Microproteins." The 5-year project aims to leverage the unique biochemical properties of microproteins, a recently discovered class of small proteins, to identify their interactions and functions across...
- The National Science Foundation Division of Environmental Biology awarded a $899,374 project grant to the University of California Irvine from September 1, 2021 to August 31, 2024. The grant supports research titled "BEE: TESTING A PHYLOGENETIC TRAIT FRAMEWORK FOR SOIL MICROBIOMES" under the Biological Sciences program (CFDA 47.074). The research aims to advance understanding of major problems confronting the nation by promoting progress in the biological sciences. Specifically, the...
The University of California, Irvine (UCI) was awarded a $1,227,751 Project Grant from the National Institutes of Health (NIH) Trans-NIH Research Support program (CFDA 93.310) to develop "Chemical Glycobiology Tools to Decipher Host-Microbiota Interactions." The project aims to discover precise molecular, cellular, and spatial factors that allow commensal and probiotic microbes to modulate host immunity, with a focus on exo- and capsular polysaccharides as key modulators of innate and adaptive immunity. The proposed research will address technical challenges in characterizing microbial polysaccharides through the development of new diversity-oriented approaches to identify host receptors, glycan motifs, cell types, and gut regions involved in microbial glycan signaling. The award period runs from August 15, 2025 to July 31, 2028.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $1.2m | 8/11/25 |