Project Grant C06OD039908
- The National Institute of General Medical Sciences (NIGMS) awarded a $314,000 Project Grant under the Biomedical Research and Research Training program (CFDA 93.859) to Cellfe, Inc. to optimize the CellFE microfluidic platform for same-day, multiplexed CRISPR-based gene editing of T cells. This innovation aims to accelerate the manufacturing of allogeneic CAR-T cell therapies by streamlining the gene editing process and addressing limitations around slow recovery times, high cytotoxicity, and...
- This $500,000 Project Grant from the National Science Foundation Division of Molecular and Cellular Biosciences, under the Biological Sciences federal grant program (CFDA 47.074), will support research to develop an end-to-end continuous manufacturing process for cell therapies using robotics and microfluidic technologies. The Georgia Tech Research Corporation will receive funding to create a more integrated workflow based on microfluidic device-enabled genetic engineering, cell expansion, and...
- This federal Project Grant award of $430,675.00 from the National Institute of General Medical Sciences (NIGMS) Biomedical Research and Research Training program (CFDA 93.859) supports research at the University of Delaware to study the dynamic interactions between cells and their mechanical microenvironments. The research aims to develop engineered material platforms that can mimic time-dependent biomechanical cues to better understand how cells respond to changes in their physical...
- This Project Grant award from the National Institute of General Medical Sciences (NIGMS) Biomedical Research and Research Training program (CFDA 93.859) provides $421,600 to The Morgridge Institute for Research, Inc. to understand how metabolic conditions influence the behavior of human cells. The key products and services to be delivered under this 5-year award include: Elucidating genetic and environmental contributions to human cell fitness and growth, leveraging innovative tools such as a...
- This Project Grant award of $406,250.00 from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859) supports research to implement a nascent extracellular matrix (ECM) model into the dynamic reciprocity of cell-ECM interactions. The overarching goal is to develop and apply engineering tools to better understand cell-cell and cell-ECM interactions within complex cellular systems, such as organoids and organ-on-chip...
- This $151,870 Project Grant award from the National Institute of General Medical Sciences (NIGMS) Biomedical Research and Research Training program (CFDA 93.859) supports the development of computational tools to identify non-canonical junctions in the SARS-CoV-2 coronavirus transcriptome. The research aims to shed light on previously missed genomic features that may be relevant for human infection and lead to the discovery of novel coronavirus proteins. The project, awarded to Rutgers...
- This $1,737,000 Project Grant awarded by the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859) supports the development of innovative single-cell genomics technologies for joint analysis of regulatory dynamics and transcriptional states. Key objectives include: Developing multiomics tools to measure rates of epigenomic changes (DNA methylation, demethylation, oxidative damage, DNA repair) and relate these to...
- The University of Colorado Anschutz Medical Campus received a $107,821 Project Grant award from the National Institutes of Health (NIH) Office of Research Infrastructure Programs (CFDA 93.351) to purchase a Sartorius CellCelector Flex System. This state-of-the-art live cell and organoid imaging and handling technology will empower cell line development, rare cell detection, and analysis for 8 investigators with diverse research interests in oncology, neuro-oncology, immunology, microbiology,...
- The National Institutes of Health (NIH) Office of Research Infrastructure Programs (ORIP) awarded a $454,942 Project Grant (CFDA 93.351) to the University of California, San Diego (UCSD) on May 15, 2025. The purpose of the grant is to provide UCSD's Human Embryonic Stem Cell Core Facility (HESCCF) with a state-of-the-art full-spectrum Cytek Aurora flow cytometer. This high-end instrument will enable HESCCF users to expand their flow cytometry analysis capabilities up to 40+ parameters and...
- This $7,999,914 Project Grant awarded by the National Institutes of Health (NIH) under the Construction Support program (CFDA 93.352) will fund the renovation and modernization of a facility at the Institute of Living (IOL) in Hartford, CT to create a new multi-modal clinical neuroscience research center. The grant will centralize IOL's ongoing and new research programs focused on discovering biological subtypes (or "biotypes") of psychiatric disorders, with the goal of advancing...
The Coriell Institute for Medical Research was awarded a $4,969,509 Project Grant from the National Institutes of Health (NIH) Office of the Director under the CFDA 93.352 Construction Support program. The funds will be used to create a 7,495 square foot Cell Engineering Center at Coriell's new headquarters facility in Camden, New Jersey. This center will enable expansion of Coriell's biobanking infrastructure and product/service offerings, including the development of stem cell lines, 3D "mini-organ" models, and other advanced research tools that complement and reduce the need for animal testing. Coriell is a nonprofit biomedical research center specializing in biorepository management, biospecimen services, and scientific research, supporting federal initiatives across disciplines like cancer, aging, and neurological disorders. This grant award will enhance Coriell's capacity to provide critical biospecimen and repository services that enable cutting-edge biomedical research.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $5.0m | 9/18/25 |