Project Grant 2542524
- This $763,328 CAREER award from the National Science Foundation's (NSF) Division of Molecular and Cellular Biosciences under the Biological Sciences program (CFDA 47.074) supports research on designing dynamic protein structures with enhanced functionality. Awarded to the Research Foundation of The City University of New York (RFCUNY), operating as the Advanced Science Research Center, on June 15, 2026, with completion targeted for May 31, 2031, the project delivers fundamental research...
- Federal Project Grant Award Summary Emory University received a $500,001 CAREER (Faculty Early Career Development) award from the National Science Foundation's Division of Chemical, Bioengineering, Environmental, and Transport Systems under the Engineering program (CFDA 47.041), effective June 1, 2026, through May 31, 2031. The award funds the development of high-precision phototoxic subtractive tissue engineering technologies that utilize spatially patterned light to selectively induce...
- Federal Grant Award Summary Georgia TECH Research Corp received a $100,000 Project Grant from the National Science Foundation's Division of Emerging Frontiers under the Biological Sciences program (CFDA 47.074), awarded July 1, 2025, with completion targeted for December 31, 2026. This collaborative research initiative, titled "ACED: Accelerating Protein Engineering with Evolution-Guided Generative AI and a Self-Driving Biofoundry," aims to develop advanced artificial intelligence (AI)...
- Federal Grant Award Summary Georgia TECH Research Corp received a $298,251 Project Grant from the National Science Foundation's Division of Biological Infrastructure under the Biological Sciences program (CFDA 47.074), effective September 1, 2025 through August 31, 2030. This CAREER award funds the development of artificial intelligence and machine learning (AI/ML) algorithms designed to address annotation inequality in protein function characterization. The research delivers computational...
- Federal Grant Award Summary The National Science Foundation's Division of Chemical, Bioengineering, Environmental, and Transport Systems awarded a Faculty Early Career Development (CAREER) grant of $549,998 to the University of Michigan on February 15, 2026, under the Engineering program (CFDA 47.041). The five-year project, scheduled for completion on January 31, 2031, will develop ultrasensitive single-molecule protein detection platforms capable of simultaneously measuring both the...
- Federal Project Grant Award Summary Duke University's Office of Research Administration received a $574,808 Project Grant from the National Science Foundation (NSF) Division of Chemical, Bioengineering, Environmental, and Transport Systems under the Engineering program (CFDA 47.041), effective May 1, 2025 through April 30, 2030. This CAREER award supports fundamental research to understand and control cellular heterogeneity in chimeric antigen receptor (CAR) T-cell populations through advanced...
- Federal Grant Award Summary This $347,628 CAREER (Faculty Early Career Development) Project Grant, awarded by the National Science Foundation's Division of Molecular and Cellular Biosciences under the Biological Sciences program (CFDA 47.074), commenced June 1, 2025, and extends through May 31, 2030. The award supports fundamental research conducted at Purdue University to elucidate the assembly, supramolecular organization, and functional mechanisms of bacterial microcompartments—specialized...
- This National Science Foundation (NSF) Engineering program (CFDA 47.041) Project Grant of $545,000 awarded May 15, 2025, supports research to enhance recombinant protein production in Komagataella pastoris (Pichia pastoris), a food-safe yeast widely utilized in biomanufacturing and biological research. The research will deliver scientific outcomes demonstrating how codon usage patterns can be exploited to maximize recombinant protein expression while simultaneously preserving host cellular...
- This CAREER award from the National Science Foundation's (NSF) Engineering program (CFDA 47.041) funds the development of an artificial nervous system enabling in-body communication between wearable and implantable bioelectronic devices. Awarded to Georgia TECH Research Corp on June 15, 2025, with $499,896 obligated through May 31, 2030, the project addresses critical limitations in existing therapeutic systems by creating optimized emitter and receiver networks that facilitate real-time...
- Federal Project Grant Award Summary The National Science Foundation (NSF) Division of Molecular and Cellular Biosciences awarded $672,000 to the Colorado School of Mines under the Biological Sciences program (CFDA 47.074) on June 1, 2026, for a project titled "CAREER: Probing Pathway Complexity of Biomolecular Assemblies Through Coarse-Grained Deep Learning Models." The award supports a five-year research initiative (through May 31, 2031) that will develop computational tools combining...
This CAREER (Faculty Early Career Development) project grant, awarded June 1, 2026, by the National Science Foundation's Division of Chemical, Bioengineering, Environmental, and Transport Systems under the Engineering program (CFDA 47.041), provides $647,941 in federal funding to Georgia Tech Research Corporation to develop innovative synthetic biology methods for creating and evolving antibodies in yeast cells. The primary deliverable is an engineered yeast system that efficiently recapitulates key aspects of natural antibody recombination and affinity maturation, leveraging cellular engineering, protein targeting, multiplex genetic engineering, and antibody yeast display technologies. This system will enable rapid generation and controlled selection of functional antibodies created from scratch in yeast, with incorporation of targeted in vivo mutation capabilities, thereby circumventing the months-long natural process that occurs in human B cells. The award also encompasses significant educational and workforce development components, including the development of project-based coursework and the creation of educational applications designed to train students in synthetic biology and biotechnology. The five-year project period (through May 31, 2031) is anticipated to generate foundational research insights applicable to the formulation of more effective disease-targeting therapeutics while advancing the broader field of antibody engineering and development.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $647.9k | 4/30/26 |