Project Grant 2534780
- The University of Kentucky Research Foundation received a $458,896 Project Grant award from the National Science Foundation Division of Chemistry on January 1, 2022 to support research differentiating the two complementary flavins in a bifurcating electron transfer flavoprotein. The two-year project will be completed by December 31, 2024. The award is being made under the Mathematical and Physical Sciences program (CFDA 47.049) of the National Science Foundation, which aims to promote progress...
- The U.S. National Science Foundation (NSF) awarded a $426,000 project grant under the Mathematical and Physical Sciences (CFDA 47.049) program to The Regents of the University of California, San Francisco (UCSF) to conduct collaborative research on developing novel protein-based materials for photosynthetic energy transduction. The multi-year project, led by Professors Michael Therien and David Beratan of Duke University and William DeGrado of UCSF, aims to design and construct protein-based...
- This $700,000 Project Grant awarded on May 1, 2025 by the National Science Foundation's (NSF) Mathematical and Physical Sciences program (CFDA 47.049) supports Professor Jeffrey Rudolf at the University of Florida in studying bacterial cytochrome P450 enzymes and their redox partners. The project aims to discover new natural products and understand the molecular interactions between P450 enzymes and their required redox partner proteins. This research will provide valuable training for...
- The National Science Foundation (NSF) awarded a $599,999 project grant under the Mathematical and Physical Sciences (CFDA 47.049) program to the University of California, Santa Barbara (UCSB) and the University of Pittsburgh. The 3-year collaborative project aims to investigate the detailed mechanisms and origins of selectivity in recently developed enzymatic reactions with unnatural electron transfer pathways. The research team, led by Professors Yang and Liu, will integrate computational tools...
- This Project Grant award from the National Science Foundation (NSF) under the Biological Sciences program (CFDA 47.074) provides $369,297 to San Francisco State University (SFSU) to develop a synthetic transhydrogenation module to enhance the production of valuable chemicals using engineered organisms. The key objectives are to: Elucidate the structural mechanisms underlying the autoregulation of the GltAB-GudB enzyme complex in Bacillus subtilis, which regulates glutamate metabolism and impacts...
- This Project Grant award of $555,000 from the National Science Foundation's (NSF) Division of Chemistry, under the Mathematical and Physical Sciences program (CFDA 47.049), supports research by Professor James Allen and Dr. Joann Williams of Arizona State University to study how proteins control proton-coupled electron transfer reactions. The researchers aim to create reversible, long-lived electron and proton transfer processes that mimic biological systems. By manipulating bacterial reaction...
- The National Science Foundation (NSF) awarded a $800,000 Project Grant under the Biological Sciences program (CFDA 47.074) to The Washington University's Office of Sponsored Research Services Division. The 3-year project aims to investigate the metabolic cooperation between a phototrophic bacterium and a methanogenic archaeon, and how this "syntrophic" interaction influences methane production and the nitrogen cycle in anoxic environments. The research will shed light on how these...
- The National Science Foundation (NSF) awarded a $479,856 Project Grant under the Mathematical and Physical Sciences program (CFDA 47.049) to the University of Kansas Center for Research Inc. The grant, awarded on September 1, 2025 with an ultimate completion date of August 31, 2028, supports the development of new manganese and iron complexes that mimic intermediates in biological metal-dependent enzymes. The goal is to use these complexes to improve proton-coupled electron-transfer reactions,...
- This Project Grant from the National Science Foundation Division of Chemistry, under the Mathematical and Physical Sciences program (CFDA 47.049), provides $131,882 to support collaborative research on electrocatalytic synthesis of heterocycles from biomass-derived furanics via immobilized first-row transition metal catalysts. Professors Yujie Sun of Vanderbilt University and De-En Jiang of the University of California, Riverside will develop electrocatalysts using coordinatively unsaturated...
- The National Science Foundation (NSF) has awarded a $450,000 Project Grant under the Mathematical and Physical Sciences program (CFDA 47.049) to the University of Louisiana at Lafayette (ULL), operating through its Office of Research. This 3-year collaborative research grant, beginning September 15, 2023, will support an investigation into the initial charge separation mechanism in Photosystem I, a critical component of photosynthesis in plants, algae, and bacteria. The research team, led by...
This Project Grant award from the National Science Foundation's (NSF) Mathematical and Physical Sciences (CFDA 47.049) program is providing $605,000 to the University of Kentucky Research Foundation to study how electron transfer bifurcation is interfaced with metabolic pathways in diverse microorganisms. The research aims to understand how microbes can convert solar energy into high-energy fuel and maximize the use of Earth-abundant, renewable materials. Key objectives include surveying a broader range of bifurcating electron transfer flavoproteins, characterizing the interactions between bifurcation and supporting recycling systems, and elucidating the mechanisms by which the proteins involved tune the reactivities of electron-transferring flavins. The project will also develop hands-on workshops and public-friendly course modules to make chemical concepts more accessible through the aesthetic appeal of plant pigments and textile art.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $605.0k | 8/25/25 |