Project Grant 2534247
- This Project Grant award for $140,390 was provided by the National Science Foundation (NSF) under the Mathematical and Physical Sciences (CFDA 47.049) federal grant program. The award supports research to develop porous peptide frameworks inspired by the modular architecture of proteins. The research aims to engineer these frameworks by appending peptides with aromatic π-stackers to guide the predictable self-assembly of the peptides into sophisticated porous materials. If successful, these...
- The National Science Foundation (NSF) has awarded a $250,000 Project Grant under the Mathematical and Physical Sciences (CFDA 47.049) program to the University of California, Merced. The grant, titled "LEAPS-MPS: EXPANDING THE PEPTIDE ASSEMBLY LANDSCAPE USING MULTIVALENT PEPTIDE MACROCYCLES WITH DESIGNABLE INTERMOLECULAR INTERFACES", supports research led by Professor Merg and his students aimed at developing new approaches for designing and constructing peptide-based nanomaterials....
- The National Science Foundation (NSF) awarded a $574,404 Project Grant to Purdue University under the Mathematical and Physical Sciences program (CFDA 47.049) to conduct research on building unique nanoscale structures using peptide building blocks. The principal investigator, Dr. Jean Chmielewski, will study how the size and shape of the resulting peptide nanostructures is controlled by the surface they are built on at the molecular level. This research aims to gain an enhanced understanding of...
- This $480,000 Project Grant award from the National Science Foundation's (NSF) Mathematical and Physical Sciences program (CFDA 47.049) supports the development of novel approaches for assembling three-dimensional protein biomaterials. The primary goal is to create "coordinated protein frameworks" (CPFs) - extended protein lattices with defined geometries and tunable distances between the assembled proteins. This work leverages non-canonical amino acids to precisely control the...
- This Project Grant awarded by the National Science Foundation (NSF) Engineering program (CFDA 47.041) will fund a collaborative research effort at the University of Colorado to study the fundamental relationships that control the assembly of solid materials from small, shape-changing ribbon-like particles. The $397,494 award, spanning from January 1, 2025 to December 31, 2027, will investigate the use of reversible physical entanglement of these shape-changing particles to create porous solid...
- This $305,983 collaborative research project, funded by the National Science Foundation's Mathematical and Physical Sciences program (CFDA 47.049), aims to establish how sequence-controlled polymers can be used for the rational design of surfactant-containing materials. The University of Massachusetts, the award recipient, will leverage sequence-defined polypeptides to modulate the assembly of surfactants into various nanostructures. The research will involve experimental work using optical...
- This $688,144 Project Grant award from the National Science Foundation's (NSF) Mathematical and Physical Sciences (CFDA 47.049) program supports a collaborative research effort led by Professors Ilya Zharov and John Conboy of the University of Utah. The project aims to elucidate the molecular-level interactions between polymer-grafted silica nanoparticles during self-assembly using sum frequency generation (SFG) vibrational spectroscopy. The researchers will systematically investigate how...
- This Project Grant award from the National Science Foundation's (NSF) Mathematical and Physical Sciences program (CFDA 47.049) provides $466,359 to The Washington University in University City, Missouri to develop a new family of porous organic frameworks. These lightweight, carbon-based crystalline materials will feature both small cavities for selectively recognizing molecules of similar sizes and larger channels for high-capacity uptake and rapid transport. The goal is to create adaptive...
- This National Science Foundation (NSF) Mathematical and Physical Sciences (CFDA 47.049) Project Grant award of $330,000 supports theoretical and computational research by the University of California, Merced to describe and understand the behavior of biologically-inspired active solids. The research aims to create models that combine mechanical and chemical factors to investigate the unique shape changes and self-organization phenomena possible in active solids, such as those found in cell...
- The U.S. National Science Foundation (NSF) awarded a $426,000 project grant under the Mathematical and Physical Sciences (CFDA 47.049) program to The Regents of the University of California, San Francisco (UCSF) to conduct collaborative research on developing novel protein-based materials for photosynthetic energy transduction. The multi-year project, led by Professors Michael Therien and David Beratan of Duke University and William DeGrado of UCSF, aims to design and construct protein-based...
This National Science Foundation (NSF) Project Grant, awarded under the CFDA 47.049 Mathematical and Physical Sciences program, provides $418,423 to the University of California, Merced (UC Merced) to establish a new synthetic route for building porous materials from peptide-based building blocks. The project aims to demonstrate how the chemical and physical features, such as pore chemistry and size, of these peptide-based porous materials can be systematically engineered by altering the peptide sequence design. The outcomes from this 3-year project, which runs from Sep 1, 2025 to Aug 31, 2028, will be packaged into assembly design rules to serve as a blueprint for creating future porous biomaterials suitable for biological and environmental applications.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $418.4k | 8/15/25 |