Project Grant 2534124
- This $741,002 federal Project Grant award from the National Science Foundation's Biological Sciences program supports the development of a novel machine learning framework for analyzing large-scale, multi-modal single-cell biological data. The project aims to construct advanced computational tools and user-friendly software to enable more effective extraction of insights and knowledge from complex single-cell datasets spanning genomics, transcriptomics, epigenomics, and proteomics. The...
- The National Science Foundation awarded a $367,636 Project Grant to the Massachusetts Institute of Technology from March 1, 2021 through February 29, 2024 under the Biological Sciences program (CFDA 47.074). The grant funds collaborative research on multidimensional single-cell phenotyping to elucidate relationships between genomes and phenotypes. The Biological Sciences program aims to advance biological knowledge and understanding of major problems through basic research. This award supports...
- The National Science Foundation (NSF) awarded a Project Grant under the Biological Sciences (CFDA 47.074) program to The Johns Hopkins University totaling $856,135. The award will fund research to develop and apply new single-molecule methods to measure protein production in individual live cells, rather than population averages. The goal is to better understand the regulatory mechanisms governing when and where protein production occurs in cells. In addition to the core research, the project...
- The National Science Foundation awarded a $749,997 project grant to The Johns Hopkins University from September 2021 through August 2025 under the Computer and Information Science and Engineering program (CFDA 47.070). This funding supports collaborative research to develop integrated analysis of single-cell and spatially resolved omics data. The Computer and Information Science and Engineering program aims to advance computing, communications, and information science through...
- This federal Project Grant award from the National Science Foundation's (NSF) Computer and Information Science and Engineering (CISE) program (CFDA 47.070) provides $277,308 to the University of Oklahoma (OU) to advance computational and statistical methods for studying single-cell genomics data in the context of tissue organization. The overarching goal is to develop novel spatial algorithms to identify gene expression patterns, gain new data-driven insights on tissue changes and...
- This Project Grant award from the National Science Foundation's (NSF) Biological Sciences program (CFDA 47.074) provides $243,764 to the University of Massachusetts Boston to create a computational framework for understanding complex biological processes. The project will develop automated methods to construct causal models from large biological datasets, enabling researchers to uncover cause-and-effect relationships that drive cellular events. This work will accelerate discoveries across...
- The National Science Foundation (NSF) awarded a $225,000 Project Grant under the Biological Sciences (CFDA 47.074) program to Carnegie Mellon University and Purdue University. The grant, awarded on August 15, 2025, will support the development of a cyberinfrastructure that enables the analysis of cryo-electron tomography (cryo-ET) data. The project aims to build an open-access, annotated database of cryo-ET images and a robust toolbox of computational methods for their analysis. The resulting...
- The National Science Foundation Division of Molecular and Cellular Biosciences awarded Northeastern University a $100,000 Project Grant under the Biological Sciences federal grant program (CFDA 47.074) to support research on "The Biophysics of Collective Cell Locomotion" from December 15, 2021 through December 31, 2023. Through this funding, Northeastern University researchers in Boston, MA will investigate the major problem of understanding the biological sciences by examining the...
- The National Science Foundation (NSF) awarded a $162,510 Project Grant under the Computer and Information Science and Engineering (CFDA 47.070) program to the University of Oklahoma to develop algorithms for scalable inference and phylodynamic analysis of tumor haplotypes using low-coverage single-cell sequencing data. The goal is to create a phylodynamic framework to jointly infer cancer phylogenetic trees and evolutionary parameters from single-cell DNA sequencing data. This will enable cancer...
- This federal Project Grant award of $946,895 from the National Science Foundation's (NSF) Division of Molecular and Cellular Biosciences (CFDA 47.074 Biological Sciences) will fund research to advance the understanding of protein phosphorylation and its role in coordinating cell division. The project aims to identify new enzymes that carry out phosphorylation and the substrate proteins they modify to ensure proper cell division. Researchers will employ computational, biochemical, proteomic,...
The National Science Foundation (NSF) awarded a $498,240 Project Grant under the Biological Sciences (CFDA 47.074) federal grant program to Northeastern University. The grant supports the development of advanced cyberinfrastructure that will enable the findable, accessible, interoperable, and reusable (FAIR) use of single-cell proteomics (SCP) data. SCP is a rapidly emerging field that allows direct measurement of proteins in individual cells. The project will develop open data standards, bioinformatics tools, and data-sharing platforms to ensure SCP data can be easily reused by researchers worldwide. This work will also provide educational opportunities for students in data science and computational biology, promote open science practices, and deliver outreach programs to improve public scientific literacy. The award period is from September 1, 2025 to August 31, 2028.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $498.2k | 8/7/25 |