Project Grant 2528400
- This Project Grant award of $275,000.00 from the National Science Foundation's (NSF) Technology, Innovation, and Partnerships (CFDA 47.084) program, supports the development of a novel platform to accelerate strain development for precision fermentation. The goal is to create an alternative means of food protein production to reduce the environmental impact of traditional livestock farming. The platform leverages machine learning and experimental biology to enable high-yield production of a...
- This Project Grant award of $575,765 from the National Science Foundation's (NSF) Division of Chemical, Bioengineering, Environmental, and Transport Systems (CFDA 47.041 Engineering) supports research to enhance the production of biochemicals from sustainable single-carbon (C1) feedstocks using bacteria. The key objectives are to understand the regulation of carbon metabolism in anaerobic acetogenic bacteria and use this knowledge to engineer them as effective producers of valuable fuels and...
- This $256,000 Project Grant was awarded by the National Science Foundation (NSF) under the Technology, Innovation, and Partnerships (CFDA 47.084) program. The award to Terragia Biofuel Inc., a for-profit organization, aims to develop innovative bioprocessing technologies for converting lignocellulosic biomass into hydrocarbon fuels and products. Specifically, the project is focused on demonstrating the feasibility of a technique called Continuous Evolution with Multiplex Natural Transformation...
- The National Science Foundation (NSF) awarded a $1,180,313 Cooperative Agreement to Bluestem Biosciences Inc., a for-profit company based in Omaha, Nebraska, under the NSF Technology, Innovation, and Partnerships (CFDA 47.084) program. The funding will support a 24-month project focused on developing an optimized yeast strain capable of efficiently producing the chemical intermediate 3-hydroxypropionic acid (3-HP) under anaerobic conditions. The broader impact of this project is to establish a...
- The National Science Foundation (NSF) awarded a Project Grant under the NSF Technology, Innovation, and Partnerships (CFDA 47.084) program to Femtofluidics Incorporated for $294,932 on January 1, 2025. The purpose of this SBIR Phase I award is to develop hardware that enables the rapid and inexpensive synthesis of DNA-encoded libraries (DELs). This technology aims to accelerate drug discovery by expediting the identification of drug candidates for challenging diseases and generating data to...
- This Project Grant award of $458,552.00 from the National Science Foundation's Engineering program (CFDA 47.041) supports research to significantly reduce the downstream processing costs associated with producing methane-derived polyhydroxyalkanoate (PHA) biopolymers. The project aims to genetically engineer methane-consuming bacteria to facilitate easier recovery of the PHA polymers, with the goal of a 5-10% reduction in capital expenditures and up to 15% in operational expenditures. Key...
- The National Science Foundation (NSF) awarded a $545,000 Project Grant under the Engineering program (CFDA 47.041) to the Trustees of Tufts College. The grant, titled "Exploiting Codon Usage Bias to Maximize the Productivity of Recombinant Komagataella pastoris (Pichia pastoris)", aims to understand how this food-safe yeast allocates resources for protein synthesis to maximize productivity. The research will focus on controlling translation elongation by evaluating the relative...
- The National Science Foundation (NSF) Division of Molecular and Cellular Biosciences and the Division of Chemical, Bioengineering, Environmental and Transport Systems awarded a $240,000 Project Grant to the University of California Irvine (UC Irvine) under the NSF Biological Sciences program (CFDA 47.074). The grant supports collaborative research to develop unnatural cofactors that can be deployed as stronger-than-nature thermodynamic driving forces in biomanufacturing processes. This is...
- This two-year, $200,000 Project Grant from the National Science Foundation's Division of Chemical, Bioengineering, Environmental, and Transport Systems will fund research at the Long Beach Research Foundation to develop multi-activity proteins for improved carbohydrate deconstruction. Specifically, the Foundation will produce and test 85 engineered multi-activity proteins containing two catalytic domains each. These proteins aim to increase biomass conversion for alternative fuels and...
- The National Science Foundation (NSF) awarded Pearl Bio, Inc., a biotechnology company, a $274,462 Project Grant under the NSF Technology, Innovation, and Partnerships program (CFDA 47.084). The grant funded the development of a next-generation biomanufacturing platform to engineer new microbial organisms and cellular machinery. This platform enables the incorporation of diverse, non-native components into proteins, creating a new class of biological materials for therapeutic development,...
This $245,300 Project Grant awarded by the National Science Foundation (NSF) under the Technology, Innovation, and Partnerships (CFDA 47.084) program aims to use synthetic biology methods to improve the production of volatile organic chemicals, primarily ethanol and acetone, by a hyperthermophile microbe. The project seeks to engineer a high-temperature microbe strain that can be feasibly used for large-scale biomanufacturing. Successful implementation of this technology has the potential to improve American fuel and chemical feedstock independence while increasing demand for domestic agricultural markets. The award was made to Integrated Dynamics, Inc., a for-profit organization located in Chicago, Illinois, with a performance period from October 1, 2025 to June 30, 2026.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $245.3k | 8/27/25 |