Project Grant 2528115
- This SBIR Phase II Cooperative Agreement, awarded by the National Science Foundation (NSF) under the Technology, Innovation, and Partnerships (CFDA 47.084) program, aims to develop a novel sprayable hydrogel sealant for managing gastrointestinal (GI) lesions and bleeding. The $1,250,000 award to Biodevek Inc., a Boston-based small business, will fund the advancement of this minimally invasive, bio-adhesive hydrogel technology designed to provide sustained lesion protection and hemostasis...
- The National Heart, Lung, and Blood Institute (NHLBI), under CFDA Program 93.837 - Cardiovascular Diseases Research, awarded a $464,229 Project Grant to Limax Biosciences Inc. to develop HEMOMAX, a biodegradable hydrogel adhesive to improve hemostasis during vascular surgery. The key objectives of this Phase I grant are to: (1) conduct comprehensive bench performance testing on HEMOMAX, including sterilization validation and endotoxin assessment, and (2) evaluate the safety and efficacy of...
- Karios Technologies LLC, a for-profit organization, received a $274,954 SBIR Phase I grant from the National Science Foundation (NSF) Technology, Innovation, and Partnerships program (CFDA 47.084) to develop a novel, ready-to-use, large volume delivery system for in situ forming biomaterials. The biomaterials are intended to serve as tissue sealants, scar tissue reducers, and vehicles for drug or cell delivery during surgical procedures. The project aims to transfer a proprietary biomaterial...
- This $999,783 Phase II Small Business Innovation Research (SBIR) cooperative agreement from the National Science Foundation (NSF) Technology, Innovation, and Partnerships (CFDA 47.084) program supports Intact Therapeutics' development of a thermogel-based drug delivery platform for the treatment of upper gastrointestinal bleeding (UGIB). Intact Therapeutics' proprietary thermogel technology aims to rapidly stop UGIB prior to endoscopic treatment, potentially reducing patient morbidity,...
- The National Science Foundation (NSF) awarded a $275,000 SBIR Phase I Project Grant under the NSF Technology, Innovation, and Partnerships (CFDA 47.084) program to Auxilium Health, Inc. located in Cleveland, OH. The project aims to develop and validate an aerogel-based wound dressing material platform with mechanical fluid management, biofilm prevention, and real-time pH-based infection detection properties. The innovative dressing material is intended to improve chronic wound care by mitigating...
- This SBIR Phase I project, funded by the National Science Foundation (NSF) Technology, Innovation, and Partnerships (TIP) program (CFDA 47.084), focuses on developing an innovative bioprinting approach to create vascular grafts that closely mimic the properties of natural blood vessels. The project aims to overcome the limitations of current synthetic and biological grafts by utilizing a specialized bioprinting process that integrates a double-network hydrogel made from a Dacron synthetic...
- The Project Grant award of $1,339,647 from the National Institute of Biomedical Imaging and Bioengineering (CFDA 93.286 - Discovery and Applied Research for Technological Innovations to Improve Human Health) aims to develop a novel pressure-sensitive adhesive (PSA) system for minimally invasive surgery (MIS). The key products or services to be delivered include an instant and reversible wet tissue adhesive tape that can adhere to wet tissues in confined surgical environments, enabling improved...
- The National Science Foundation (NSF) awarded a $305,000 Small Business Innovation Research (SBIR) Phase I grant under the NSF Technology, Innovation, and Partnerships (CFDA 47.084) program to Novaurum Biosciences Incorporated in Somerville, MA. The project aims to develop a novel mammalian cell-based nano-biological coating for implantable medical devices that can inhibit biofilm formation and protect against bacterial infections, including antibiotic-resistant strains, while promoting...
- This Project Grant award, valued at $117,562 and provided by the National Science Foundation's (NSF) Mathematical and Physical Sciences Program (CFDA 47.049), supports fundamental research to develop a new class of bioadhesive implants for medical applications. The research aims to address limitations of existing hydrogel bioadhesives, such as mechanical mismatch with tissues and unstable adhesion, which can lead to complications in prolonged implantation. The project will determine optimal...
- This $944,676 Project Grant award from the National Heart, Lung, and Blood Institute (CFDA 93.837 - Cardiovascular Diseases Research) supports the development of a novel platelet-inspired nanotechnology called Synthoplate (SP) to restore hemostasis in patients on antiplatelet agents. The technology aims to address the critical unmet need for a readily available, donor-independent therapeutic that can effectively restore hemostatic function in traumatic brain injury (TBI) patients on P2Y12...
This $305,000 Phase I Small Business Innovation Research (SBIR) grant awarded by the National Science Foundation (CFDA 47.084 - NSF Technology, Innovation, and Partnerships) to Limax Biosciences Inc. in Boston, MA aims to develop a novel hemostatic hydrogel adhesive for advanced surgical bleeding control. The project will focus on optimizing the bioinspired HEMOMAX hydrogel, which can achieve adhesion energies 100-1,000 times greater than existing commercial tissue adhesives, to rapidly and effectively seal bleeding wounds even in wet environments. This project has the potential to save up to 70,000 lives annually in the U.S. by addressing a major unmet need in surgical hemostasis, which can significantly increase patient recovery times and medical costs. The effort will also contribute to job creation, workforce development, and intellectual property generation in the field of biomedical engineering and surgical technologies.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $305.0k | 7/25/25 |