Project Grant 2528087
- This Project Grant from the National Science Foundation's Technology, Innovation, and Partnerships program (CFDA 47.084) provides $275,000 to Dcan Biosciences LLC to develop an advanced microfluidic system for cancer diagnosis and monitoring. The system aims to isolate and assess circulating tumor cells (CTCs) and CTC clusters (CTCCs) from patient blood samples to enable highly sensitive and accurate liquid biopsies. Key objectives include designing a hybrid microfluidic device for...
- The National Science Foundation (NSF) awarded a $305,000 Project Grant under the NSF Technology, Innovation, and Partnerships (CFDA 47.084) program to Innotech Precision Medicine, Inc., a woman-owned small business and minority-owned corporation. The grant supports the development and validation of a portable diagnostic system that detects cancer markers for risk and progression in saliva. The project aims to create a fully integrated microfluidic device that combines multiple biomarker...
- This National Science Foundation (NSF) Technology, Innovation, and Partnerships (CFDA 47.084) Project Grant award of $275,000 to Cerflux Inc. aims to develop a personalized cancer treatment screening platform. The project will establish guidelines for handling solid tumor biopsy samples, generate 3D bioprinted tumor models for validation, and demonstrate the platform's ability to match patients with the most effective cancer treatments before treatment begins. This innovative approach has the...
- The National Science Foundation awarded a $275,000 Project Grant to Oraliva, Inc. under the Technology, Innovation, and Partnerships program to develop a portable, programmable single cell cytology platform for the early detection of epithelial cancers. The platform will combine microfluidics and artificial intelligence to classify potentially cancerous tissue in near real-time through multiparameter single-cell analysis and automated evaluation. The objectives are to link different clinical...
- This $274,594 Project Grant award from the National Science Foundation (NSF) Technology, Innovation, and Partnerships (CFDA 47.084) program supports research and development of an innovative technology for cancer diagnosis and treatment. The project aims to improve molecular profiling and clinical laboratory testing of cancer samples by optimizing microdissection techniques. The research will focus on modeling and optimizing the opto-thermal-mechanical interactions involved in microdissection to...
- This National Science Foundation Project Grant of $255,995 supported Encapsulate Inc. to develop an automated biochip platform for personalized cancer screening under the NSF Technology, Innovation, and Partnerships program (CFDA 47.084). The award period was from May 15, 2022 to April 30, 2023. The platform will grow patient-derived cancer cells outside the body on biochips to screen them against chemotherapy drugs. This addresses the problem that over 70% of cancer patients undergo ineffective...
- Micropure Genomics Inc. received a $274,199 Project Grant award from the National Science Foundation to advance methods for rapid, end-to-end sample preparation for sequencing applications. Under the NSF Technology, Innovation, and Partnerships program (CFDA 47.084), the company will develop an automated process relying on electro-hydrodynamic trapping to isolate genomic material like DNA or RNA from cells in a flow cartridge. The process aims to significantly reduce preparation time while...
- This $1,213,619 Cooperative Agreement award from the National Science Foundation (NSF) under the Technology, Innovation, and Partnerships (CFDA 47.084) program supports the development of a precision oncology platform by Encapsulate Inc., a small disadvantaged business located in Farmington, CT. The project aims to create an integrated microfluidic system that utilizes patient-derived tumor samples to predict individual responses to cancer treatments, including chemotherapy drugs. By maintaining...
- This National Science Foundation (NSF) Technology, Innovation, and Partnerships (CFDA 47.084) Project Grant award of $275,000 to Beken Bio, Inc. aims to develop a highly sensitive, minimally invasive laboratory test to detect early-stage ovarian cancer by assaying relevant biomarkers on circulating extracellular vesicles in patient plasma. The project will utilize a novel technology to identify key proteins in extracellular vesicles from various ovarian cancer subtypes and employ a machine...
- This Small Business Innovation Research (SBIR) Phase I project, awarded by the National Science Foundation (NSF) through its Technology, Innovation, and Partnerships (TIP) program (CFDA 47.084), aims to develop a rapid diagnostic test for identifying sepsis-causing pathogens in plasma samples using available digital PCR hardware. The proposed DNA-based technology seeks to comprehensively detect and quantify a wide range of pathogens from small blood volumes, a critical capability for...
This SBIR Phase I project, awarded by the National Science Foundation (NSF) Technology, Innovation, and Partnerships (CFDA 47.084) program, aims to develop an automated system that streamlines the preparation of liquid biopsy samples for cancer testing. The $305,000 award, provided to Avant Genomics, LLC, will fund the creation of a microfluidic-based system that automates the bisulfite conversion process, a critical step in epigenetic analysis of circulating tumor DNA. This innovation seeks to address the limitations of the current manual, labor-intensive, and error-prone sample preparation workflow, making cancer screening faster, more cost-effective, and more accessible, particularly for low- and mid-throughput clinics and laboratories. If successful, this technology has the potential to enable earlier cancer detection, improve treatment monitoring, and ultimately enhance patient outcomes while reducing the economic burden of cancer care.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $305.0k | 7/25/25 |