Project Grant 2522259
- The National Science Foundation (NSF) awarded a $200,000 Project Grant under the Biological Sciences (CFDA 47.074) Federal Grant Program to Cornell University to develop tools and infrastructure for improving the efficiency of whole genome sequencing (WGS) data analysis. The project aims to optimize the Genotype Representation Graph (GRG) data structure for modern parallel computing architectures, particularly GPUs, to handle the dynamic nature of genomic computations. Additionally, the...
- This $794,457 federal Project Grant award from the National Science Foundation's (NSF) Biological Sciences program (CFDA 47.074) will support the development of new genetic analysis tools. The goal is to incorporate molecular and cellular biology knowledge, such as gene expression patterns and regulatory networks, directly into statistical models used to map genes, predict traits, and simulate changes in the genotype-to-phenotype relationships. The research will be conducted using simulated...
- This $836,598 Project Grant, awarded by the National Science Foundation (NSF) under the Biological Sciences Federal Grant Program (CFDA 47.074), supports research to develop tools for sequencing expanded genetic alphabets and studying how natural biological systems interact with these unnatural DNA letters. The research aims to improve the generalizability and accuracy of next-generation sequencing for unnatural base pairs, develop new methods for measuring polymerase replication fidelity, and...
- This Project Grant award of $174,999 from the National Science Foundation (NSF) under the Mathematical and Physical Sciences program (CFDA 47.049) will support the development of new statistical tools to enhance the power and precision of discovering disease-associated genes. The project aims to uncover subtle genetic signals that might otherwise be missed by integrating diverse sources of genomic information and improving how prior knowledge and statistical evidence are combined. The...
- This $300,000 Project Grant awarded by the National Science Foundation (NSF) Biological Sciences program (CFDA 47.074) supports the development of probabilistic string similarity sketching software for metagenomics and RNA-seq analysis. The research aims to provide rigorous mathematical proofs for the analysis techniques used in genome alignment and apply these methods to the discovery of new protein variants and measurement of RNA levels in cells. The project will analyze the average-case...
- This federal Project Grant award of $423,750.00 was provided by the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859). The grant, awarded on May 1, 2025, supports a research project at New York University (NYU) School of Medicine to develop new conceptual and statistical approaches that integrate molecular, cellular, and population genetics to better understand the genetic basis of complex human traits and diseases....
- This federal Project Grant award, valued at $541,574.00 and awarded on January 15, 2025, is funded by the National Science Foundation (NSF) under the Biological Sciences (CFDA 47.074) Federal Grant Program. The project, titled "COLLABORATIVE RESEARCH: NSF/MCB-BSF: THE EFFECT OF TRANSCRIPTION FACTOR BINDING ON UV LESION ACCUMULATION", aims to determine whether transcription factor binding to DNA makes it more susceptible to damage or impedes DNA repair, leading to increased genomic...
- This $993,446 Project Grant award from the National Human Genome Research Institute (CFDA 93.172 Human Genome Research) supports the development of statistical and machine learning approaches to decode the regulatory activity underlying disease variants, link variants to genes in relevant cell types, and identify disease-critical cooperative programs of genes and genomic elements. The goal is to produce computational tools and workflows that can identify and rank functionally disease-critical...
- This $2,963,428 Project Grant award from the National Science Foundation's Biological Sciences program (CFDA 47.074) aims to develop critical infrastructure and tools for interpreting genomic data. The project will create high-quality genome assembly workflows, comprehensive documentation, and interactive training materials to make these advanced genomic analysis capabilities accessible to a wide audience of biology researchers. This will enable downstream discoveries in areas such as...
- The National Science Foundation awarded a $276,000 Project Grant to an individual located in Seattle, Washington under the Biological Sciences federal grant program (CFDA 47.074). The two-year award will fund research defining the link between genetic variation in human populations and messenger RNA stability. The fellow will use high-throughput experimental and computational approaches to identify amino acid motifs that alter mRNA stability. This includes a novel massively parallel knock-in...
This federal Project Grant award of $245,753.00 by the National Science Foundation's Social, Behavioral, and Economic Sciences program (CFDA 47.075) supports research into the translation of scientific research, specifically human genomic analysis, into a medical tool for newborn genomic screening. The project investigates the scientific research, biotechnology actors, and other interested parties driving this development, as well as its effects on patients, healthcare systems, and society. Using mixed methods, the research analyzes grants, publications, media coverage, and interviews to understand how new areas of modern medical science and biotechnology are developed and translated into medical tools. The project aims to inform scholars, stakeholders, decision-makers, and the public on the ethical and societal contexts of this emerging field. No sub-awards are planned under this award, which has a performance period from August 1, 2025 to July 31, 2027.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $245.8k | 7/28/25 |