Project Grant 2516357
- The University of Wisconsin-Madison will receive $500,000 from the National Science Foundation under a three-year Project Grant to study chemical and biological interception of cell-cell communication in gram-positive bacteria. The grant, awarded August 1, 2021 and set to conclude July 31, 2024, falls under the NSF's Mathematical and Physical Sciences program (CFDA 47.049). Through this funding, University of Wisconsin researchers in the Department of Chemistry will investigate how gram-positive...
- This federal Project Grant award of $1,000,000.00 from the National Science Foundation's Biological Sciences program (CFDA 47.074) was provided to The Trustees of Princeton University to study "Quorum Sensing Across Scales and Between Domains". The project aims to investigate bacterial communication processes, known as quorum sensing, to better understand how bacteria can synchronize behavior and potentially control harmful pathogens or promote beneficial bacteria. Key objectives...
- The National Science Foundation Division of Molecular and Cellular Biosciences awarded a $668,913 Project Grant to the University of Massachusetts Office of Grant & Contract Administration to support research titled "Collaborative Research: Model-Guided Design of Bacterial Interspecies Interactions and Trans-Organismic Communication in Living Intercellular Circuits." The award aims to advance understanding of interspecies biochemical cell-cell communication in natural microbial...
- The National Science Foundation awarded a $934,613 project grant to Princeton University on July 1, 2021, with a completion date of June 30, 2024. The grant supports research under the Biological Sciences program (CFDA 47.074) to study quorum sensing control of bacterial biofilm formation and dispersal. The funding will allow Princeton University researchers to advance scientific understanding of how bacteria communicate to form biofilms and disperse, with the goal of gaining fundamental...
- The National Science Foundation (NSF) awarded a $552,000 Project Grant under the Mathematical and Physical Sciences program (CFDA 47.049) to the University of Nevada, Reno (UNR). The 3-year grant, starting on August 1, 2023, supports research led by Professor Tal-Gan to study the interplay between different bacterial communication pathways in Streptococcus mutans. The project aims to characterize how diverse quorum sensing circuits within the same bacterial species affect one another and...
- The National Science Foundation Division of Molecular and Cellular Biosciences awarded a $629,896 Project Grant to the University of Wisconsin-Madison on February 15, 2021 with a completion date of January 31, 2026. The grant supports research under the Biological Sciences program (CFDA 47.074) to advance understanding of heterogeneous decision-making in individual microbes and populations through synthetic approaches. As the official program description indicates, the Biological Sciences...
- This federal Project Grant award of $339,999, provided by the National Science Foundation (NSF) under the Mathematical and Physical Sciences (CFDA 47.049) program, supports collaborative research to study the spatiotemporal dynamics of intercellular signaling in engineered multicellular bacterial systems. The research aims to develop novel mathematical modeling techniques that can better predict the behavior of spatially extended synthetic bacterial populations, which have potential applications...
- This Project Grant award for $150,000.00, provided by the National Science Foundation (NSF) under the Mathematical and Physical Sciences (CFDA 47.049) program, supports fundamental research on the multiscale dynamics of bacterial flagella movement through complex biological fluids like mucus. The research combines mathematical modeling, computer simulations, and laboratory experiments to investigate how bacteria swim through viscoelastic fluids, which is crucial for understanding infections in...
- This $300,000 Project Grant awarded by the National Science Foundation (NSF) Engineering program (CFDA 47.041) supports a collaborative research project focused on understanding the mechanics and morphogenesis of bacterial biofilms. The award, with an effective date of December 1, 2025 and a completion date of November 30, 2028, will enable researchers at Yale University to conduct detailed observations and theoretical modeling of biofilm growth under varying environmental conditions, such as...
- The National Science Foundation (NSF) awarded a $626,831 Project Grant under its Biological Sciences program (CFDA 47.074) to the University of Wisconsin-Milwaukee (UWM) to conduct collaborative research on the molecular mechanisms behind how certain bacteria use light-sensing proteins called phytochromes to regulate essential developmental processes. The project aims to use advanced structural biology techniques like cryo-electron microscopy and time-resolved X-ray crystallography to study...
This $600,000 Project Grant awarded by the National Science Foundation's (NSF) Division of Chemistry, under the Mathematical and Physical Sciences (CFDA 47.049) federal grant program, supports Professor Helen Blackwell at the University of Wisconsin-Madison to investigate the chemical signals bacteria use to communicate and coordinate group behaviors. The research aims to better understand the structures and functions of these bacterial signaling molecules, known as autoinducing peptides, and to develop synthetic versions that can be used to activate or inhibit bacterial communication pathways. This work provides fundamental insights into bacterial quorum sensing, which is the process by which bacteria coordinate group behaviors at high cell densities, and has potential applications in preventing bacterial infections and disease. The project also includes public outreach activities to educate the general public about the role of bacteria and their chemical signals in the environment. The grant period runs from September 1, 2025 to August 31, 2028.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $600.0k | 8/20/25 |