Project Grant 2507422
- This National Science Foundation Project Grant of $249,532 supports the development of an inline particle monitoring system for sterile liquid filtration in food and beverage manufacturing via holographic imaging. Funded through the NSF Engineering Directorate's Engineering program (CFDA 47.041), the project advances digital holographic sensing and machine learning image processing to detect and characterize contaminants in real-time with single particle sensitivity. This rapid, label-free...
- This SBIR Phase I award from the National Science Foundation (NSF) Technology, Innovation, and Partnerships (CFDA 47.084) program provides $304,780 to Nanoplasmonics LLC to develop a plasmonically enhanced molecular imprinted polymer sensor system for rapid, on-site detection of mycotoxins in the food supply. The primary technical innovations include synthetic molecular imprinted polymers that function as artificial antibodies for selective mycotoxin detection, combined with plasmonic...
- The National Science Foundation (NSF) awarded a $305,000 Small Business Innovation Research (SBIR) Phase I project grant under the NSF Technology, Innovation, and Partnerships (CFDA 47.084) program to Primary Bioscience, Inc. The project aims to develop an ultra-sensitive biosensor capable of protein analysis at the single-molecule level. The biosensor utilizes a nanopatterned chip with a proprietary scaffold material to bind and immobilize molecular targets, which are then detected using...
- This Small Business Innovation Research (SBIR) Phase I project, awarded by the National Science Foundation (NSF) under the Technology, Innovation, and Partnerships (TIP) program (CFDA 47.084), aims to develop optimized high surface area functionalized nanomaterials for parts per billion (PPB) gas sensing using machine learning models. The $274,991 award to Atmosense, Inc., a minority-owned small business located in San Diego, CA, will fund the research and development of advanced materials...
- The National Science Foundation (NSF) awarded a Project Grant under the NSF Technology, Innovation, and Partnerships (CFDA 47.084) program to Femtofluidics Incorporated for $294,932 on January 1, 2025. The purpose of this SBIR Phase I award is to develop hardware that enables the rapid and inexpensive synthesis of DNA-encoded libraries (DELs). This technology aims to accelerate drug discovery by expediting the identification of drug candidates for challenging diseases and generating data to...
- This $274,990 Small Business Innovation Research (SBIR) Phase I award from the National Science Foundation (CFDA 47.084 - NSF Technology, Innovation, and Partnerships) supports the development of a physics-based machine learning platform for predicting the crystal structure of small drug molecules. The technology aims to accelerate and reduce the cost of early-stage pharmaceutical research and development by computationally analyzing the crystal structure properties that determine key...
- This National Science Foundation (NSF) Technology, Innovation, and Partnerships (CFDA 47.084) Project Grant award for $275,000 will support the development of a plasmonic nanopore sensor device for quality control of adeno-associated viruses (AAVs) used in gene therapy. The proposed device will enable accurate characterization of AAV payload (single-stranded DNA, double-stranded DNA, or empty) at low, pre-scale-up concentrations to optimize formulations. The project aims to demonstrate the...
- This National Science Foundation (NSF) Technology, Innovation, and Partnerships (CFDA 47.084) Project Grant award to Wave Lumina Inc. will develop a portable, field-deployable device for rapid, real-time detection of per- and polyfluoroalkyl substances (PFAS) in water. The $305,000 award, effective May 15, 2025 through April 30, 2026, aims to create an affordable sensor system that integrates surface-enhanced Raman spectroscopy (SERS) and artificial intelligence (AI) for detecting PFAS at...
- This Small Business Innovation Research (SBIR) Phase I Project Grant awarded by the National Science Foundation (CFDA 47.084 - NSF Technology, Innovation, and Partnerships) focuses on advancing a novel acoustic sensor-based diagnostic platform for rapid identification and antimicrobial susceptibility testing of pathogens, particularly for urinary tract infections. The project aims to achieve three key technical objectives: (1) demonstrate accurate antimicrobial susceptibility testing (AST) at...
- This STTR Phase I Project Grant, awarded by the National Science Foundation's (NSF) Technology, Innovation, and Partnerships (TIP) program (CFDA 47.084), provides $305,000.00 to Leonine Technologies Inc. to develop and validate a hybrid control system for polymer injection molding. The system combines real-time in-mold sensing with machine-state data to model melt-state dynamics and enable predictive quality control. The anticipated commercial impact is improved efficiency, reliability, and...
This SBIR Phase I project awarded by the National Science Foundation (NSF) under the Technology, Innovation, and Partnerships (CFDA 47.084) program will develop a novel inline sensor system to monitor particulate matter and sterility in continuous manufacturing processes for injectable drugs. The $304,972 award, effective from October 1, 2025 to September 30, 2026, will fund the creation of a compact, low-cost sensor that leverages digital inline holography and deep learning to detect contaminants in real-time. This transformational approach aims to strengthen U.S. competitiveness in smart manufacturing and quality assurance, potentially reducing recall and quality control costs by up to 20% for large pharmaceutical manufacturers. The intellectual merit of the project lies in the development of the dual-function sensor system, which will enable earlier identification of contaminants, reduce production downtime, minimize waste, and improve product safety. The broader impacts include applications in food safety, environmental monitoring, and biodefense.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $305.0k | 8/27/25 |