This $1,634,839 Project Grant awarded by the National Science Foundation (NSF) under the Mathematical and Physical Sciences (CFDA 47.049) program aims to revolutionize live-cell imaging through the development of nanodiamond quantum sensors. The grant, awarded to Purdue University with a subcontract to the University of Texas at Dallas, will enable the fabrication of scalable nanodiamond sensors and their integration with advanced light-sheet microscopy techniques. This will achieve high spatiotemporal resolution and low phototoxicity, allowing for detailed 4D imaging of complex biological processes such as cancer immunotherapy and cellular membrane potentials. The project encompasses educational and outreach programs to foster diversity in quantum science and engineering fields. This NSF-funded effort will advance the understanding of fundamental life processes and has broad implications for biomedical research and applications.
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