Project Grant 2447743
- This Project Grant award of $300,000 from the National Science Foundation (NSF) Integrative Activities program (CFDA 47.083) supports the development and experimental validation of computational tools for simulation-guided design of DNA nanostructures and molecular systems. The project aims to integrate high-level and low-level computational models to enable more powerful and user-friendly multiscale modeling frameworks for DNA nanotechnology. Key objectives include parameterizing coarse-grained...
- The National Science Foundation (NSF) Division of Materials Research awarded a $499,999 Project Grant to Arizona State University (ASU) under the Mathematical and Physical Sciences program (CFDA 47.049). The three-year grant project aims to: 1) create 3D DNA crystal scaffolds to host and determine the structure of RNA aptamers; 2) attach and immobilize functional proteins like enzymes within the crystal lattices to develop catalytic materials; and 3) develop sub-100 nm DNA nano-crystals to...
- This $236,662 National Science Foundation award through the Mathematical and Physical Sciences program (CFDA 47.049) funds research at Emory University to develop novel biomimetic materials capable of simultaneously encoding both nucleic acid and protein information codes to control assembly and function. Specifically, the award supports exploration of "bilingual biopolymers" using peptide nucleic acid as a scaffold to direct structure based on both peptide and nucleic acid...
- The National Science Foundation (NSF) awarded a $2,000,000 Project Grant under the Mathematical and Physical Sciences program (CFDA 47.049) to the Massachusetts Institute of Technology (MIT) for the "DATA-DRIVEN HIGH-THROUGHPUT DESIGN OF DNA NANOMATERIALS FOR NEXT-GENERATION OPTOELECTRONIC AND QUANTUM TECHNOLOGIES" project. This 4-year project aims to develop a machine learning-guided, high-throughput in silico screening platform to accelerate the discovery of functional chromophore-...
- This Project Grant award from the National Science Foundation's (NSF) Mathematical and Physical Sciences program (CFDA 47.049) provides $441,848 to the University of California, Santa Barbara to conduct research on the fundamental science of "complex coacervates", which are microscopic droplets formed from charged polymers. The research aims to develop a mechanistic understanding of how these materials form and their unique properties, such as the ability to encapsulate and deliver...
- This Project Grant award from the National Science Foundation's Mathematical and Physical Sciences program (CFDA 47.049), in the amount of $642,000, will fund research at Northwestern University to develop novel hybrid protein-DNA supramolecular structures. The key objectives are to: (1) design generalizable strategies for site-specific DNA functionalization to control proteins in 1D arrays; (2) create dynamic, DNA-driven 2D protein lattices; and (3) utilize DNA interactions to facilitate...
- The National Science Foundation (NSF) awarded a $230,000 Project Grant under the Mathematical and Physical Sciences program (CFDA 47.049) to the University of North Carolina at Chapel Hill for the period of August 1, 2023 to July 31, 2026. The research project will investigate and validate a new class of Cosserat rod models to describe the stretch-limiting behavior of biological fibers like DNA and RNA. Key expected deliverables include determining the fundamental properties of these models from...
- The National Science Foundation awarded a $501,269 Project Grant to Stanford University under the Mathematical and Physical Sciences program (CFDA 47.049). The grant will fund theoretical and computational modeling of supercoiling, topology, and active fluctuations in chromosomal organization and dynamics from September 2021 through August 2024. As part of the Mathematical and Physical Sciences program's goal of strengthening the Nation's scientific enterprise through increased understanding...
- This $223,362 Project Grant award from the National Science Foundation's Computer and Information Science and Engineering (CFDA 47.070) program supports collaborative research by Arizona State University to develop new mathematical tools and frameworks for "Algorithmic Shape Encoding" - using DNA molecules and self-assembling 3D structures to encode and manipulate information at the nanoscale. The research aims to create breakthroughs in areas like self-assembling materials,...
- The National Science Foundation Division of Emerging Frontiers awarded a $3,000,000 Project Grant to the University of California, Los Angeles under the Biological Sciences federal grant program (CFDA 47.074) to support research on DNA and RNA condensate droplets for programmable separation and manufacture of biomolecules. The four-year award running from December 2021 to November 2025 will fund the development of portable educational modules on condensate science and molecular programming as...
This Project Grant award from the National Science Foundation's (NSF) Mathematical and Physical Sciences program (CFDA 47.049) provides $364,550 to Amherst College to study the rules for designing active DNA materials using condensing agents. The key objectives are to investigate how condensing agents can bend, loop, and reconfigure DNA in order to impart desirable properties like decreased size, increased stability, and altered electrical conductivity. The research will be conducted entirely by undergraduate researchers, providing an educational opportunity to train the next generation of scientists and engineers. The project aims to develop insights that could impact applications such as immunotherapies, carbon capture, tissue engineering, and nanorobotics. The award has an initial term from August 1, 2025 to July 31, 2029.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $364.6k | 7/16/25 |