Project Grant 2440587
- This federal Project Grant award from the National Science Foundation (NSF) Engineering program (CFDA 47.041) provides $199,867 to the University of Washington to develop an innovative approach for long-term cryopreservation of organs using ice-free vitrification and single-mode electromagnetic resonance (SMER) heating. The project aims to overcome barriers in organ cryopreservation by advancing vitrification and EM heating technologies to enable fast and uniform rewarming of cryopreserved...
- The Regents of the University of Minnesota received a $299,992 Project Grant award from the National Science Foundation to support the development of next-generation cryopreservation media for natural killer cells under the NSF Technology, Innovation, and Partnerships program (CFDA 47.084). The two-year project period runs from May 1, 2021 through April 30, 2023. The NSF Technology, Innovation, and Partnerships program seeks to advance science and engineering research and innovation leading to...
- This federal Project Grant award from the National Institute of General Medical Sciences (NIGMS) Biomedical Research and Research Training Program (CFDA 93.859) provides $306,852 to Mitegen, LLC, a manufacturer of advanced scientific instruments and technologies located in Lansing, New York. The funding will support the development and validation of innovative cryopreservation technology that automates the soaking, cooling, and warming processes for small biological samples such as oocytes and...
- This three-year, $162,238 Project Grant from the National Science Foundation's Mathematical and Physical Sciences program (CFDA 47.049) supports collaborative research between Yale University, Stony Brook University, and researchers at examining and developing biomimetic peptides that inhibit ice formation. The researchers aim to understand and mimic antifreeze proteins in nature to generate synthetic antifreeze molecules for applications such as biological material preservation, food processing...
- This Project Grant award from the National Science Foundation's (NSF) Engineering program (CFDA 47.041) provides $463,746 to the University of Puerto Rico Medical Sciences Campus (UPR-MSC) to study an innovative continuous crystallizer concept. The objective is to develop robust, scalable, and miniaturized equipment for pharmaceutical manufacturing that can improve resilience to supply chain disruptions and better meet fluctuating market needs. The research seeks to advance continuous...
- This $200,000 Project Grant award from the National Science Foundation's (NSF) Mathematical and Physical Sciences program (CFDA 47.049) supports a collaborative research effort led by New York University (NYU) School of Medicine. The project aims to enhance the design of fluorinated protein fibers and hydrogels for medical applications. Key objectives include: 1) generating coiled-coil fluorinated fibers for controlled drug delivery, 2) developing temperature-responsive fluorinated hydrogels,...
- The National Science Foundation (NSF) awarded a $401,490 Project Grant under the Engineering program (CFDA 47.041) to the University of Massachusetts (UMass) to develop a modular toolset for imaging cellular metabolites using fluorogenic RNA riboswitches. The project aims to engineer fluorescent probes that can selectively detect and measure key metabolites, such as sugars and fatty acids, within living cells in real-time. This novel approach will enhance research in human health, nutrition,...
- This Project Grant award from the National Science Foundation (NSF) Engineering program (CFDA 47.041) provides $450,000.00 to the Massachusetts Institute of Technology (MIT) to study how the structures of synthetic molecules can be tailored to recognize and bind to specific target molecules for detection in biosensors and potential therapeutics. The project aims to develop computational methods to predict the interactions between nanoparticle "corona" phases and target analytes,...
- The National Science Foundation (NSF) Biological Sciences (CFDA 47.074) Federal Grant Program awarded The Trustees of Columbia University in the City of New York a $1,200,000 Project Grant on March 15, 2025 to develop and apply a method of time-resolved cryo-electron microscopy (cryo-EM) to diverse biological molecules of medical importance. The project aims to use newly designed PDMS-based microfluidic chips to apply the time-resolved cryo-EM sample preparation technique, which has been...
- This $420,000 Project Grant award from the National Science Foundation's Engineering program (CFDA 47.041) supports collaborative research on the effects of microgravity conditions on crystal growth and particle self-assembly during directional solidification of solutions. The research aims to reveal the subtle forces involved in these processes when gravity is removed, and compare the structural features obtained in microgravity versus on Earth. The research will integrate experimental...
The National Science Foundation (NSF) Engineering program (CFDA 47.041) has awarded a $650,267 Project Grant to The General Hospital Corporation, doing business as Massachusetts General Hospital (MGH), to identify and characterize low toxicity cryoprotective solutions for cryopreservation. The 5-year award, beginning on July 15, 2025, aims to use high-throughput screening to examine a larger chemical space of glass-forming molecules and discover cryoprotectant formulations with minimal toxicity. The project will also incorporate educational initiatives to increase awareness and understanding of cryopreservation, as well as efforts to engage community college students in the laboratory research. The goal is to address the major limitation of cryoprotectant toxicity in cryopreservation technologies, particularly for vitrification approaches that preserve tissue architecture.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $650.3k | 7/17/25 |