This $376,301 project grant awarded by the National Science Foundation's Biological Sciences program (CFDA 47.074) supports research at the University of Rochester aimed at developing a practical approach for controlling and stabilizing microbial communities. The project leverages plasmid conjugation to dynamically balance microbial growth rates and composition, creating programmable microbial populations that can maintain stability across diverse conditions. Key objectives include computational...
This National Science Foundation Project Grant award of $776,213 provides funding over five years from January 2023 through December 2027 for research and educational efforts focused on developing novel statistical methods to detect parallel evolution in microbiome metagenomic data. The grant is awarded under the Biological Sciences program (CFDA 47.074) to support basic biological research that strengthens the nation's scientific enterprise. Specifically, the University of California, Los...
This Project Grant award of $502,674.00 from the National Science Foundation's (NSF) Biological Sciences (CFDA 47.074) Federal Grant Program supports research to investigate how gut microbes from different mammalian hosts vary in their capacity to use and transform nitrogen, an essential nutrient that impacts microbial growth and activity. The project aims to computationally reconstruct the microbial nitrogen transformation networks across mammalian hosts and experimentally study the adaptive...
This Project Grant award from the National Science Foundation's (NSF) Biological Sciences (CFDA 47.074) program provides $1,239,776 to the University of Nevada, Reno (UNR) to conduct collaborative research on the role of gene copy number variation in determining detoxification capacity, individual fitness, and population dynamics of a vertebrate herbivore. The key objectives of this 4-year research project are to: 1) identify individual copy number variation in detoxification genes, 2)...
The National Science Foundation (NSF) awarded a $188,491 Project Grant under the Biological Sciences (CFDA 47.074) federal grant program to the University of New Mexico. This 5-year grant, effective January 1, 2025 through December 31, 2029, will support collaborative research to investigate how microbial symbionts influence the health and stability of host plants, including grasses important for ranching and landscaping. The research team will use long-term demographic data from a unique...
The National Science Foundation awarded a $276,000 Project Grant under the Biological Sciences federal grant program (CFDA 47.074) to support a postdoctoral fellowship in biology from September 1, 2022 to August 31, 2024. The fellowship will fund the collection and analysis of gut microbiome samples from over 3,300 animal species, representing the most comprehensive dataset to date. This will allow for improved understanding of the origins and ecological controls of gut microbiomes across the...
The National Science Foundation awarded a two-year, $138,000 Project Grant to support research titled "Extremes in the Interplay: The Development and Effects of Gut Microorganisms within Earth's Largest Terrestrial Species." The grant was awarded on August 1, 2021 under the Biological Sciences program (CFDA 47.074) to be conducted in Fort Collins, Colorado through July 31, 2023. The $138k grant will fund research examining the gut microbiomes of large terrestrial species and how...
This $671,535 Project Grant awarded by the National Science Foundation (NSF) Biological Sciences program (CFDA 47.074) supports research examining the recovery trajectories of prey communities after the removal of non-native predator species, such as fish, from mountain lakes in the Sierra Nevada region of California. The key objectives are to elucidate the connections between taxonomic and functional recovery of these ecosystems, identify indicators of community vulnerability based on...
The National Science Foundation awarded a $207,000 Project Grant to support research titled "Diet and the Microbiome as Drivers of Host Tolerance and Resistance to Parasites" from February 1, 2021 through January 31, 2024. The grant was awarded under the Biological Sciences program (CFDA 47.074) to conduct basic research promoting advancement in the biological sciences. Funding will support the grantee's investigation into how diet and the gut microbiome influence an organism's...
The University of South Florida (USF) received a $681,876 Project Grant from the National Science Foundation (NSF) Division of Integrative Organismal Systems under the Biological Sciences grant program (CFDA 47.074). The grant will fund a collaborative research project to investigate how prophages (viruses that infect bacteria) influence the structure and function of animal microbiomes, specifically in Ciona robusta (an invertebrate chordate) and Danio rerio (zebrafish). The project will...
This $1,101,668 Project Grant award from the National Science Foundation's Biological Sciences (CFDA 47.074) Federal Grant Program will support research at the University of Nevada, Reno to investigate the genetic basis of host-microbiome interactions using the Mexican tetra fish as a model system. The key objectives are to: 1) use metagenomic sequencing and transcriptomics to compare gut microbiota composition and host gene expression across different fish ecotypes, 2) conduct quantitative trait locus mapping in hybrid fish to identify host genetic loci associated with microbiota and host traits, and 3) use CRISPR/Cas9 genome editing to functionally test the effects of specific candidate genetic variants. The research aims to reveal the molecular mechanisms linking host genetics and microbiome composition, and clarify the relationship between microbiomes and vertebrate metabolic traits. The award also includes educational and outreach components, such as a new graduate course module, an undergraduate research mentorship program, and a public exhibit at the UNR Museum of Natural History. The project period runs from September 2025 through August 2030.