Project Grant 2434652
- The University of California, Santa Barbara will receive $500,000 from the National Science Foundation Division of Chemistry under the Mathematical and Physical Sciences program (CFDA 47.049) from September 1, 2021 to August 31, 2024. The funding will support the project "Harnessing the Reactivity of Sulfur: From Novel S-Atom Transfer Reagents to Sulfide-Protected Nanoclusters," which aims to advance the understanding of sulfur chemistry through development of new sulfur-transfer...
- This $139,543 Project Grant award from the National Science Foundation's (NSF) Mathematical and Physical Sciences program (CFDA 47.049) supports the development of "Extended Lifetime Peroxynitrite-Responsive Probes (XL-PRPs)" - a new class of biomaterials designed for long-term, non-invasive monitoring of peroxynitrite, a biomarker linked to chronic disease severity. The research, conducted by the University of California, Santa Barbara, aims to create materials that can continuously...
- This $575,000 Project Grant from the National Science Foundation's Division of Chemistry, under the Mathematical and Physical Sciences program (CFDA 47.049), will fund research at the University of California, San Diego to synthesize and study the reactivity of unusual main group elements stabilized by transition metal isocyanide complexes, from July 1, 2023 to June 30, 2026. Specifically, Professor Joshua S. Figueroa will manipulate boron monofluoride and diphosphorus molecules, which are...
- This Project Grant award from the National Science Foundation (NSF) under the Biological Sciences program (CFDA 47.074) provides $369,297 to San Francisco State University (SFSU) to develop a synthetic transhydrogenation module to enhance the production of valuable chemicals using engineered organisms. The key objectives are to: Elucidate the structural mechanisms underlying the autoregulation of the GltAB-GudB enzyme complex in Bacillus subtilis, which regulates glutamate metabolism and impacts...
- This Project Grant award, funded by the National Science Foundation (NSF) Division of Chemistry under the Mathematical and Physical Sciences Federal Grant Program (CFDA 47.049), supports research at the University of Texas at Austin to study how the secondary coordination sphere (SCS) affects the activity of copper enzymes. The $594,870 award from August 1, 2024 to July 31, 2027 employs a novel biosynthetic approach to modulate copper enzyme activity, with potential applications in areas like...
- This CAREER Project Grant, awarded by the National Science Foundation's (NSF) Mathematical and Physical Sciences program (CFDA 47.049), provides $785,000 in funding to Professor Pier Alexandre Champagne at the New Jersey Institute of Technology (NJIT) to advance the chemical understanding of reactive sulfur species. The project employs a combination of experimental and computational techniques to: 1) access new synthetic donors of reactive sulfur species, 2) use these donors to probe the...
- This Project Grant award from the National Science Foundation's (NSF) Mathematical and Physical Sciences program (CFDA 47.049) to the University of California, Berkeley provides $780,000 in funding to investigate the molecular mechanisms of oxygen-dependent enzymes and develop synthetic mimics. The key objectives are to study a class of oxygen-dependent decarboxylase enzymes that utilize iron, manganese, or mixed metal active sites. This research aims to elucidate the critical oxygen-activated...
- The National Science Foundation (NSF), through its Mathematical and Physical Sciences program (CFDA 47.049), awarded a $234,925 Project Grant to the University of Florida. The funding supports research conducted by Professor Kate Carroll to investigate post-translational protein cysteine modifications and the chemical reactivity of sulfur. The research explores how different cysteine thiol group modifications impact the properties of the sulfur atom, which is essential for understanding the role...
- This $542,333 federal Project Grant award from the National Science Foundation's (NSF) Mathematical and Physical Sciences program supports research by Professor Eunsuk Kim of Brown University to develop a new class of catalysts capable of efficiently inserting or removing sulfur from molecules. The project will focus on synthesizing and comparing the catalytic activities of two groups of molybdenum-containing catalysts with tridentate and tetradentate ligand frameworks. The goal is to create...
- The National Science Foundation (NSF) Division of Chemistry awarded a $375,000 project grant under the Mathematical and Physical Sciences (CFDA 47.049) program to support a collaborative research effort between the University of Michigan and the University of Colorado Boulder. The grant, awarded from July 1, 2024 to June 30, 2027, aims to study the role of surface-bound ligands on metal catalysts in the direct synthesis of hydrogen peroxide, an important industrial chemical. The research team,...
This $249,793 Project Grant awarded by the National Science Foundation's (NSF) Division of Chemistry under the Mathematical and Physical Sciences program supports the development of new ruthenium-based chemical tools to study the biological role of the gaseous signaling molecule hydrogen sulfide (H2S). The research team at the University of California, Santa Barbara aims to leverage the redox and photochemical properties of ruthenium coordination complexes to create H2S-releasing agents that can be selectively activated. These new tools will enable researchers to better understand how H2S regulates critical biological processes and its potential therapeutic applications for conditions like heart disease, stroke, and cancer. Additionally, the project will develop educational activities for high school STEM teachers to highlight the importance of H2S in human biology. This award runs from July 1, 2024 to June 30, 2025 and does not include any planned sub-awards.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $249.8k | 9/4/24 |