This $501,538 National Science Foundation Project Grant under the Mathematical and Physical Sciences program (CFDA 47.049) funds research at Stony Brook University from July 1, 2022 to June 30, 2025 to develop nanocellulose-enabled nanocomposites for sustainable water remediation. The objectives are to understand how to incorporate model cationic metal oxide nanoparticles into anionic cellulose nanofiber scaffolds of varying charge density and fibrillation to create new functional...
This Project Grant award of $100,689 from the National Science Foundation's (NSF) Mathematical and Physical Sciences program supports research at North Carolina State University (NC State) to study the self-assembly of renewable cellulose nanocrystals (CNCs) on solid surfaces. The goal is to elucidate how substrate properties and drying conditions affect the assembly and color-generating capabilities of these CNC structures, with the aim of developing sustainable materials and bio-inspired...
The National Science Foundation (NSF) awarded a Project Grant of $653,629 to Northeastern University on February 1, 2024 under the Engineering program (CFDA 47.041). The objectives of this 5-year project are to elucidate and optimize the binding affinity between collectins (a class of immune system proteins) and glycans (sugar structures found on pathogens), with the goal of enhancing early detection and response to viral infections like influenza. The research will employ an interdisciplinary...
This Project Grant award from the National Science Foundation (NSF) under the Engineering program (CFDA 47.041) provides $199,998 to the University of North Carolina at Greensboro (UNC-G) to develop synthetic antigen-presenting cells (SAPCs) that can precisely control the immune response. The project aims to elucidate how the size of SAPCs influences their function, with the goal of developing and evaluating size-tunable SAPCs that enhance T cell activation and adaptive immune response for...
The National Science Foundation Division of Chemical, Bioengineering, Environmental, and Transport Systems awarded a $639,361 Project Grant to The Washington University to investigate the effects of nanomaterial chirality on immune cells and innate immunity from June 15, 2021 to May 31, 2026. This award will fund research under the NSF Engineering program (CFDA #47.041) to study how the handedness of nanoparticles, also known as chirality, impacts immune cell function and the body's innate...
The National Science Foundation (NSF) awarded a $498,000 Project Grant under its Mathematical and Physical Sciences (MPS) program to The Research Foundation for the State University of New York (RF SUNY) for the development of cell-penetrating monobodies. The 3-year project, beginning March 2024, will explore innovative approaches to engineer monobodies - antibody-like proteins - with enhanced cell permeability for potential therapeutic applications. Key objectives include using computational...
This National Science Foundation Project Grant of $436,084 supports research at Carnegie Mellon University from May 2022 through April 2025 under the Mathematical and Physical Sciences program (CFDA 47.049). The award will fund the development of novel methods to control interactions between polymer and nanomaterial constituents in polymer nanocomposites. Specifically, the grantee will synthesize brush particle model systems and characterize the structure evolution of liquid-crystal phase...
This $315,657 National Science Foundation award under the Mathematical and Physical Sciences program (CFDA 47.049) supports the development of synthetic mucin polymers that mimic natural mucus. The Research Foundation of the City University of New York will lead a collaborative effort with the University of Pennsylvania to create new biomimetic polymers through systematic study of homopolymer, random copolymer, and triblock copolymer compositions. Researchers will investigate the relationship...
This Project Grant award from the National Science Foundation's (NSF) Engineering program (CFDA 47.041) provides $353,941 to The Research Foundation for the State University of New York, doing business as Stony Brook University, to support research on understanding and controlling the physical adhesion and aggregation of nanomaterials in liquid environments. The key objectives are to develop a predictive model for nanoparticle adhesion by considering the effects of solvent-induced...
The National Science Foundation awarded North Carolina State University $525,836 under the Mathematical and Physical Sciences program (CFDA 47.049) for a three-year project grant completing July 2025. The university will research self-organizing nucleic acid supramolecular assemblies with stimuli-responsive properties. Specifically, the project aims to develop a toolkit for constructing responsive nanoparticle-based materials using rationally designed RNAs as modular building blocks. Researchers...
This National Science Foundation (NSF) Project Grant award under the Mathematical and Physical Sciences program (CFDA 47.049) provides $468,731 to The Research Foundation for the State University of New York (RFSUNY) to investigate the immunological response and mechanisms of cellulose nanocrystals (CNCs). The research aims to functionalize CNCs with cationic polymers to study their cellular uptake, organelle interactions, and ability to modulate immune responses without cytotoxicity. Key objectives include elucidating the relationship between CNC physicochemical properties and immunomodulatory effects, laying the groundwork for future in vivo studies, and enhancing research opportunities for underrepresented and first-generation STEM students at SUNY Plattsburgh. The award period is from September 1, 2024 to August 31, 2027. No sub-awards are planned under this grant.