This federal Project Grant award, funded by the National Science Foundation's (NSF) Mathematical and Physical Sciences program (CFDA 47.049), supports collaborative research by professors Eriks Rozners of SUNY at Binghamton and James A. Mackay of Elizabethtown College. The $465,000 grant, awarded on August 15, 2024, focuses on developing new peptide nucleic acid (PNA) nucleobases capable of sequence-selective recognition of non-coding RNA. The research aims to uncover new methods for molecular recognition of biologically significant non-coding RNA, which plays important yet not fully understood roles in regulating biological processes. The project seeks to address the long-standing challenge of targeting double-stranded RNA and enable applications such as imaging and functional control of regulatory RNA, designer riboswitches for synthetic biology, and inhibition of biologically important RNA for fundamental studies. The grant also supports interdisciplinary collaborative research, training, and development of a diverse STEM workforce.
Mod # | Description | Reason For Modification | Federal Obligation (Click to sort descending) | Date (Click to sort ascending) |
|---|---|---|---|---|
| Not listed | $465.0k | 8/7/24 |