This National Science Foundation (NSF) Biological Sciences program (CFDA 47.074) Project Grant award of $289,171 to Michigan State University (MSU) aims to investigate how a class of small-molecule compounds called dipeptides control the activity of the central carbon metabolism of plants. The research project, titled "Functional Characterization of the Enzyme Dipeptide Interaction Network and Its Role in the Regulation of Arabidopsis Carbon Metabolism", leverages in vitro binding assays, enzymatic activity characterization, metabolomic analysis, and 13C metabolic flux analysis to elucidate the regulatory role of dipeptide-enzyme interactions in plant metabolism. The award, which runs from March 2024 through July 2025, will also provide research training opportunities for high school students, undergraduates, and post-doctoral associates. The findings from this project are expected to shed light on how organisms regulate their metabolism in response to environmental changes, as well as potentially generate knowledge applicable to human and animal health.
Mod # | Description | Reason For Modification | Federal Obligation (Click to sort descending) | Date (Click to sort ascending) |
|---|---|---|---|---|
| Not listed | $289.2k | 5/7/24 |