Project Grant 2425586
- This $1,155,315 Project Grant award from the National Science Foundation (NSF) Biological Sciences (CFDA 47.074) program supports research to examine the role of redox signaling in regulating the highly adaptable phototransduction signaling cascade in the Drosophila (fruit fly) visual system. The project aims to understand how blue light-induced redox changes in key phototransduction proteins can modulate the sensitivity and frequency response of this G-protein coupled receptor (GPCR) pathway,...
- This Project Grant award of $1,140,828 was provided by the National Science Foundation (NSF) Biological Sciences program (CFDA 47.074) to The Trustees of Columbia University in the City of New York, effective August 1, 2024. The purpose of the award is to generate novel network analysis tools to elucidate the functional logic of 3D vision circuits in the Drosophila (fruit fly) brain. The project aims to shed light on the relationship between microsaccades (small-scale eye movements) and 3D...
- This $238,681 National Science Foundation project grant under the Biological Sciences program (CFDA 47.074) funds research into the genetic architecture of exploration behavior in Drosophila at the University of Houston-Downtown. The researchers will use novel arena exploration assays and integrated genetic approaches to identify genes and neurons responsible for neophilia, or attraction to novel stimuli. Specifically, they will determine dopamine signaling requirements for exploratory...
- The National Science Foundation (NSF) awarded a $444,362 Project Grant under the Biological Sciences program (CFDA 47.074) to the University of Vermont & State Agricultural College, to be completed by April 30, 2027. This research project aims to investigate amino acid taste coding mechanisms and modulation in the fruit fly, Drosophila melanogaster. The primary objectives are to: 1) identify physiological factors that modulate amino acid taste response, 2) uncover the repertoire of cells and...
- This $660,000 federal Project Grant award from the National Science Foundation (NSF) Biological Sciences program (CFDA 47.074) supports research at the University of Southern California (USC) on how RNA editing regulates synaptic plasticity and behavioral adaptations in the fruit fly Drosophila melanogaster. The project aims to investigate how RNA editing of glutamate-gated chloride and voltage-gated calcium channels impacts neural circuit function, synaptic plasticity, and organismal behaviors....
- This Project Grant award of $270,000.00 from the National Science Foundation's Biological Sciences (CFDA 47.074) program funds a postdoctoral research fellowship focused on understanding the "cost of complexity" in multifunctional rhodopsin genes from cyanobacteria. The research seeks to determine how maintaining multiple functions, such as proton pumping and light absorption, impacts the ability of these genes to adapt to changing environmental conditions. The project will...
- This three-year, $750,000 project grant from the National Science Foundation's Biological Sciences program (CFDA 47.074) will fund research into the genetic architecture of exploration behavior in Drosophila. The grantee, University of Mississippi, will use novel arena exploration assays and integrated genetic approaches to identify genes and neurons responsible for neophilia, or attraction to novel stimuli. Researchers will determine dopamine signaling requirements for exploratory behavior...
- This $722,198 Project Grant awarded September 1, 2025, by the National Science Foundation (NSF) Division of Molecular and Cellular Biosciences under the Biological Sciences program (CFDA 47.074) supports research at the College of the Holy Cross investigating orphan gene function in Drosophila melanogaster sperm maturation and fertilization. The research will deliver scientific outputs including functional characterization of genes required for sperm head shaping and egg entry, cross-species...
- Cornell University was awarded a $1,000,000 project grant from the National Science Foundation Division of Molecular and Cellular Biosciences to support research titled "Engineering Photosensory Proteins Through the Better Understanding and Control of Proton-Coupled Electron Transfer Reactions." The award period is from August 1, 2021 through July 31, 2025. The grant funding will support basic research conducted under the Biological Sciences program (CFDA 47.074) to advance...
- This Project Grant award of $502,563.00 from the National Science Foundation's (NSF) Biological Sciences (CFDA 47.074) program to Villanova University supports a research project investigating how larval neurons in the Drosophila fruit fly are reprogrammed to enable stage-appropriate adult behaviors. The project will leverage Drosophila as a model system to study the cellular and molecular mechanisms underlying the transformation of juvenile neurons into circuits that support adult-specific...
This $888,757 Project Grant was awarded on July 1, 2024 by the National Science Foundation (NSF) under the Biological Sciences program (CFDA 47.074) to Weill Medical College of Cornell University. The project will explore an unexpected, chromophore-independent function of the opsin protein in fruit flies (Drosophila melanogaster), which appears to play a critical role in the homeostasis and viability of both photoreceptor and mechanoreceptor cells. The research aims to characterize opsin's phospholipid scrambling activity, determine the molecular mechanism, and assess its impact on sensory receptor structure, function, and animal behavior. This collaborative US-German project will provide fundamental insights into the ancestral and multifaceted roles of opsin proteins beyond their well-known function in vision. The findings may have broader implications for understanding how unconjugated opsins can directly influence cell biology and physiology.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $888.8k | 5/22/24 |